Conference Notes 4-17-2012

Conference Notes 4-17-2012

PAQUETTE   STUDY GUIDE SPECIAL PATIENTS

One year risk of death after a fall in the elderly is 50%.

Heroin users: Cotton fever is due to unknown pyrogen effect.  Thought to be due to particulate matter from cotton or gram neg endotoxin.  However,  even patients who don’t use cotton to filter their heroin get cotton fever. So cause is unknown.  Fever resolves spontaneously.

Patients over 65yo account for 30% of trauma deaths even though they only account for 20% of total trauma patients.

Patients over age 80 have chest pain as the presenting complaint for AMI less than 50% of the time. SOB is more common.

Myositis ossificans (heterotpic ossification) usually found in chronically immobilized patients. Can be painful.   Usually around the hip/knee/femur/shoulder.

Post traumatic syringomyelia: ascending spinal cord lesion in a patients who’s neuro deficit had been previously stable.

STRASBURGER   HIV EMERGENCIES

1.2 million people in US are living with HIV infection.   1/5 people are unaware of their HIV infection.

17,000 people died from AIDS in 2009.

HIV deaths peaked around 1995.  

AIDS:  CD4 count less than 200 or an AIDs defining illness.  

CD4 count >500 is an immunocompetent patient.    CD4 200-499 is indeterminate so look for AIDS defining illness and consider CD4 %.

CD4% is a more reliable measurement than the CD4 count because it varies less.  Normal CD4% is 32-68%.

www.aidsmeds.com   is a good reference website for side effects and drug interactions of ART (anti-retroviral therapy).   UCSF post exposure prophylaxis hotline can help you make decisions for starting prophylactic therapy after body fluid exposure.   Other good website hivinsite.ucsf.edu.

General approach to HIV/AIDS patient: Find out CD4 count, CD4 trend, viral load, opportunistic infections/medication side effects.

AIDs patients who need CT: CD4<200, fever and  nuero findings or stiff neck.   Follow CT with LP.    If patient has a CD4 count >200 you can do LP without prior CT if no focal deficits or headache.    Absolute lymphocyte count= WBC count X %lymphocytes=>2000 then CD4 count is most likely over 200.  If less than 2000 CD4 count may be less than 200.  Have low threshold for doing LP in pt’s with neuro complaints.

Toxoplasmosis may have ring enhancing lesions on head CT.

Cryptococcus Neoformans: usually CD4 count is <100 but not always.  Have chronic meningitis picture or prolonged headache.   CT is usually unremarkable.  Serum cryptococcal antigen is 95% sensitive and may be useful in the patient refusing LP.  CSF cryptococcal antigen is 100% sensitive and specific. India ink staining is only 60-80% sensitive.   Treat with amphoB and flucytosine.  

Respiratory infections: most common are bronchitis or uri.   Keep guard up for bacterial pneumonia and PCP pneumonia.   Bacterial pneumonia due to strep pneumo is most common.   PCP is the most common opportunistic infection. 

PCP pneumonia: chronic cough, hypoxia with exertion.   Walk them on a pulse ox and see if their sats drop.   ABG can help if paO2 is <70 or AA gradient is >35 signifies severe PCP.   Serum LDH can help identify PCP pneumonia.   1/3 of patients will have a nl CXR.   Can also have a focal infiltrate. CT that does not show ground glass appearance is unlikely to be PCP.

Diarrheal illness: Get stool sample for lab testing.   CD4>200 and labs look ok, and they look well, they can go home on cipro/flagyl.   If not then admit.

CMV retinitis: CD4 count usually less than 50.  Blindness in 30%.  Fundoscopy shows cotton wool like findings.  ART does not reverse disease but just slows it down.

Retinal  varicella zoster can also occur in patients with very low CD4 counts

HIV patients have accelerated progression of  coronary heart disease.  HIV should be considered a CAD risk factor.     

Immune Reconstitution Inflammatory Syndrome (IRIS): Rapid CD4 cell count increase  or rapid decrease in viral load.  Can happen within several weeks of starting ART.   Due to underlying infection that the immune system was previously not responding to.   Treat infection like PCP prior to starting ART.  Steroids also can diminish the symptoms of IRIS.

Health Department Clinics can provide free HIV testing for patients.

ANGELA ROMERO    PERFECT SERVE

GARRETT-HAUSER     ETHICS

Elder abuse: 4 felony convictions in and Kane and Cook counties in past 18 months for physical abuse and neglect. 

NH Abuse: Psychiatric patients and and sexual felons in NH population.    2 elderly alzheimers got into fight and one died.  The NH owner and staff are being prosecuted for murder/manslaughter.  NH cannot give psychiatric meds (geodon) for dementia.

Case #1: Is withdrawing care the same as murder?   The right of a competent individual to refuse any form of care is absolute.  Power of attorney also has the right to refuse care for a patient.  In some states, surrogates have similar power to refuse care.   We have a withdrawl of care form to use in ED if you want to withdraw care.  Need terminal condition, permanent unconsciousness, incurable or irreversible condition.    So answer is no, withdrawing care is not the same as murder.  Withdrawing care is not the cause of death but rather returning patient to condition of illness that will result in death.    In a DNR situation, there is no difference in not initiating treatment and withdrawing treatment. 

Case #2  13 yo girl with vaginal bleeding and dangling umbilical cord with no fetus.   Pt will not say where  baby is.   Baby was in garbage dumpster.   To whom do you have a duty as an ER doc?  You have duty to patient and to baby both ethically and legally.  Long discussion on this case but consensus felt  probably smart move would be to place mom in psychiatric care rather than sending her directly to jail. 

Case#3    How do we manage patients with chronic pain issues and drug seeking behavior?  10% of general population has substance abuse problems.   Top 3 medical specialties  with substance abuse are EM, anesthesia, and psychiatry.  Oak Forest  Hospital has a free urgent care 24/7.  This clinic can give patients access to Cook County Clinics (pain clinic).

WILLIAMSON   NEXT LECTURE  FISH TOXINS

Anaphylactic Shellfish Reaction:  Type 1 IGE immune mediated response.  Can patients with shellfish allergy get IV contrast?   Yes very safe.   Shellfish allergy is to the shell not to iodine.

Shellfish poisoning:  4 syndromes diarrheal/ amnestic reaction/neurotoxic/paralytic (sodium channel blockade) multiple cases identified in Alaska.  Pt’s have to be intubated sometimes.

Scromboid: Bacterial overgrowth in improperly stored fish producing histidine.  Can be indistinguishable from allergic reaction.  Tx with antihistamines.

Ciguatera: activation of sodium channels.   Onset 3-6 hours after ingestion.  Symptoms are paresthesias, dental pain and paradoxical temperature reversal.   Iv mannitol can be tried.

Fugu:  Tetradotoxin binds sodium channels resulting in ascending paralysis.  Supportive care and charcoal decontamination of gut are treatments.

Stingray: Venom has no specific antidote.  Get an xray for retained fb. Give prophylactic levoquin.

Mercury: Fish consumption is most common cause.  Symptoms include fatigue,  sensory impairment.  Dimercaprol is treatment.

PATEL SAEM CPC CASE PRESENTATION

Neuromuscular causes of weakness: Brain, Cord, NM junction, Muscle disorders.

Periodic Paralysis causes acute weakness due to  channelopathy.

Familial Hypokalemic Periodic Paralyssis: white race,

Thyrotoxic Periodic Paralysis:  Acquired disorder, age 20-50, Asian males.  Carbo load can precipitate an acute episode.  Ekg may show U waves.  Treat with beta blockers and possibly potassium.   Hypokalemia and labs c/w hyperthyroidism confirms diagnosis.   

Conference Notes 4-10-2012

Conference Notes 4-10-2012   (Sorry for missing 4-3-2012 but I was in Atlanta for CORD)

BRAD KUTKA      CPC Case Presentation    

BEAU WILLISON/DENNIS RYAN   ORAL BOARDS

Case 1: Ascending Cholangitis :   Patient had Charcot’s Triad of Fever/Pain/Jaundice.   Reynold’s Pentad adds altered mental status and hypotension.  Treated with antibiotics and ERCP.

Case 2:Fitz Hugh Curtis.    Pt had PID Symptoms with RUQ pain.  Treated with iv Rocephin and Iv Doxy/ Azithromycin.

Case 3: Disseminated Zoster in a lymphoma patient on chemotherapy.   Treated with IV Acyclovir.  Panculture for neutropenia.   Cover with Cefipime as well.

ANDREA CARLSON    TOXIC MELTDOWNS

The hypothalamus triggers sweating in response to heat.  As you sweat, your serum osmolarity goes up.  At a certain point, high osmolarity will trigger the hypothalamus to decrease sweat losses to conserve fluids in body.

TCA’s can cause seizures, sweat gland dysfunction both factors in hyperthermia

Cocaine associated deaths are more frequent on hot days.

Hypothermia when sustained and severe causes denaturation of proteins and enzymes.

Hypothermia is the most important negative prognostic indicator for a drug overdose.

Serotonin Syndrome: Serotonergic medication AND  4 major or 3 major and 2 minor criteria.  Altered consciousness, mood change, coma, tremor, shivering, hyperreflexia, fever, rigidity, sweating, restlessness.  3 aspects of the syndrome: 1. Cognitive /behavioral  2. Autonomic changes  3. Neuromuscular findings.  Most common findings for these three arms are: confusion, fever, myoclonus. Common drugs: SSRI’s, amphetamines, Cocaine, tramadol, DXM, lithium, MAOI’s, methylene blue (multiple case reports), linezolid, metoclopramide, prochlorperazine.

Cyproheptadine is an old antihistamine.  Direct serotonin antagonist. Anecdotal evidence of improved survival in serotonin syndrome.  PO forms only available.

Neuroleptic Malignant Syndrome: due to dopamine deficit.  Slower in onset than Serotonin syndrome.  Altered mental status and rigidity precede hyperthermia and autonomic instability.   Bradykinesia and “lead pipe rigidity”  are key neuro findings.

For both SS and NMS you gotta cool the patient.   Control seizures,  give benzos, give Dantrolene (dantrolene is a skeletal muscle relaxant and can make a pt weak but not paralyzed).  Bromocriptine for NMS, Cyproheptadine for SS.   Use other cooling measures like fans and misters.  No reports yet of using cool guard to bring down pt’s temp.   

TONY GRIPPO   TRAUMATIC BRAIN DEATH

Uniform Death Act  1981 makes brain death equivalent to cardiovascular death.

Prerequisites: Know cause of coma, normothermia, no drug intoxication/poisoning.  ETOH < 80.  No treatable metabolic causes.   BP>100systolic.

Exam: Coma; completely unresponsive to noxious stimuli.     Absent Brain Reflexes; no papillary light reflex/no corneal reflex/no ocular movement to cold calorics or doll’s eyes/response to painful stimuli above the neck/no jaw jerk/no gag or cough with suctioning.      Apnea;Vent disconnected, o2 given via tracheal canula.  If after  10 minutes pCo2 of 60 or greater and no breath that is positive for brain death.  Need two tests to be definitive.   If apnea test is inconclusive you can do nuclear medicine testing or cerebral angiography.   Nuclear medicine scan shows “empty light bulb” and “hot nose” findings when positive for brain death.

Lazarus reflex: There are some spinal reflexes even though the patient is brain dead.  Neck flexion can cause upper extremity flexion even though brain death is present.   Cremasteric reflex is preserved. There are other toe and finger reflexes that persist after brain death as well.

You have to wait 72 hours after therapeutic hypothermia (some say 6 days) before you can start considering for brain death.

Brain dead patients are the source of 50% of renal transplants and majority of extra renal organ transplants.   

Supporting the brain dead patient to maintain organ perfusion  should include volume infusion, pressor management,  and  hormone replacement therapy.   Dopamine first  and  then vasopression if needed are  the recommended pressors.  Amiodarone is the recommended antiarrythmic.   Hormonal resuscitation includes T3, Vasopressin, Methylprenisolone, and Insulin.

MARK HINTON   M&M

Pt on Coumadin falls and hits head. Subtle mental status changes.  Initial CT was neg.  INR was prolonged to 5 range.  Pt came back 1-2 days later for increased mental status changes and ataxia and renal insufficiency.  Family notes on second visit that pt has  been having multiple falls.  Pt found to be digoxin toxic. 

Digoxin toxicity:

Sources of error: minimizing problems by patient.   Recall biases,  Attending/Resident discrepencies.  Anchor bias,  premature closure.

William Withering discovered digoxin in 1785.  Treated dropsy.

Foxglove, oleander, and lily of the valley are botanical sources of digoxin.  You can also get digoxin toxic from licking the skin of toads (also hallucigenic).

Digoxin is mostly eliminated renally.

Ekg changes with therapeutic digoxin level, lateral/inferior  st depression with downsloping st segment and inverted t wave.   

First symptoms of overdose are somnolence, dizziness, and confusion.

Causes of toxicity: overdose, renal insufficiency, and drug interations (amiodarone, verapamil, vytorin, other statins, macrolides).

EKG changes in toxicity: pvc’s, any svt with av block, pat with block is pathognomonic, bidirectional V-tach, sinus bradycardia, slow afib,  regularized afib,

Severity of hyperkalemia correlates with mortality.

Xanthopsia: yellow vision.   Did Van Gogh suffer from digoxin toxicity?  He painted his doctor sitting with a foxglove plant nearby.

Treat hyperkalemia with  standard treatement insulin/dextrose, bicarb, kayexelate.  Calcium now thought to be ok for hyperkalemia.    Digibind treats the digoxin overdose and the hyperkalemia.   Digibind works in about 30-60 minutes.   Digibind is safe in kids down to 12 weeks old.

Conference Notes 3-27-2012

CONFERENCE NOTES 3-27-2012

RESIDENT TOWN HALL MEETING

JIM MALETICH  5 SLIDE FOLLOW UP

Pt presented with antero-lat STEMI and stroke symptoms.   DDX:dissection/endocarditis/prior mi with clot and embolism.

CTA was neg for dissection.  CT head showed some sign of stroke.

TPA was given

1% of MI patients will have stroke in 24 days.   Anterior MI is a risk factor for stroke.

0.1% of STEMI’s are caused by dissection.

ADAM WISE   5 SLIDE FOLLOW UP

14mo child with fever to 39.7 dx’d with viral illness and dc’d.  Came back 5 hours later with purpuric rash and LP showed meningitis.

<3mo: ecoli, GBS, listeria.  Tx: Cefotaxime and  ampicllin

>3mo: strep pneumo, neisseria, staph aureus.  Tx: ceftriaxone and vanco

Relationship with parents and good instructions are key to making sure parents brought child back to ER.   Parents impression of child’s condition is more sensitive than your clinical eval sometimes.

PAARUL CHANDRA  WILDERNESS EM

Signaling for help: highest ground is best,  SOS three short/three long/three short, three fires in triangle shape, mirror signaling.

SAM splint is a versatile and mobile splint material.

When splinting in wilderness, try to gently realign fracture fragments.

Be sure to pad your splints because using ski poles or sticks is not comfortable for patient.

SPLINTING LAB WITH MAKE SHIFT MATERIALS

ANNA LOUGHLIN   DISLOCATIONS

96% of shoulder dislocations are anterior

Hill Sachs Deformity: impaction type fx on humeral head

If pt has an associated humeral neck fx with dislocation there is increased risk of avascular necrosis.

Intra-articular injection of 20ml of lidocaine can provide adequate anesthesia to perform reduction.

Posterior shoulder dislocation associated with seizure and lightning strike.  Much less common. Subtle signs of dislocation. Light bulb sign is when humeral head has the contour of a light bulb.

Luxatio Erecta: Inferior shoulder dislocation. Humerus is directed upward. Reduction is traction/counter traction

90% of hip dislocations are posterior.   Look for other injuries because these are high energy dislocations.   Patients can have sciatic nerve injury with posterior dislocations.

Femoral nerve injury can occur with Anterior dislocations

Shenton’s line: continuous curve from femoral neck to superior pubic ramus.  If not continuous suggests dislocation.

Hip dislocations do better with very prompt reduction.  It is an emergency.

Knee dislocation is a true ortho emergency as well.  Got to look for popliteal artery injury and check ABI’s.  ABI’s should be >0.9.  If ABI less than 0.9 then get angio or CT angio.   Tibial nerve or common peroneal nerves can also be injured.

JIM MCKEAN  OSTEOFIBROMA

When kids have chronic dull knee pain look for malignant lesions with xray

BRIAN KESSEN

Pt coded.  After resuscitation EKG shows IRBBB.  PE considered and pt sent to CT.  Pt had recent SAH.

Chest CT showed bilat pe.  Ct head shows improved SAH.  Heparin started, pt was 13days after SAH. 

Pt  later had IR thrombectomy.  She did well.

EKG findings of PE: S1Q3T3,  Anterior T wave inversions,  IRBBB and tachycardia.    EKG has relatively poor  sensitivity/specificity for PE.

TPA contraindications mnemonic: TPA IS BAD

Trauma, pericarditis, active bleeding, intracranial pathology, bp >180, allergy, dissection

CHRISTINE KULSTAD  JEOPARDY  TRAUMA

Lactate is a good marker of resuscitation status.  Base deficit can be used similarly with increasing negativity correlating with worsening outcomes.

Perimortem c-section should be done within 5 minutes of cardiac arrest.  Use large midline incision.  Make small uterine incison and extend with scissors

Pregnant woman with pneumothorax put tube in a higher rib space than normal because diaphragm is higher.

 Chest tube output: 15ml/kg  immediate   or 4ml/kg/hr  indicate need for surgery in kids.   In adults it is 1500ml immediate and 200ml/hr/4hours.

1:1:1 units prbc’s/ffp/cry is indicated for massive transfusion.

Antibiotics are indicated for open depressed, sinus related skull fractures and pneumocephalus. Tx with rocepin and vanco.

Head injury in pt on Coumadin.  Should always check INR. If INR is supratherapuetic, consider observation.

Impending herniation: Tx with mild hyperventilation with pco2=30-35, mannitol 0.25-1g/kg

Retrobulbar hematoma:  Retina can only tolerate ischemia for 90 minutes.  Do lateral canthotomy.

Zygomaticomaxillary fx: check facial sensation in multiple places, good eye exam, check jaw movement, extra ocular movement.

Fx of superior roof requires admission because it risks brain injury.   Fx’s of inferior and medial orbital walls can be repaired up to 2 weeks after injury.

Open jaw fx’s should get IV antibiotics and Oral Surgery consult, and admission.

Anogenital reflexes:anal wink, cremasteric reflex, bulbocavernosis reflex.

Neurogenic shock is hypotension due to cord injury,   Spinal Shock is physiologic loss of reflexes below spinal cord injury

Central cord syndrome: upper extremity more weak than lower extremity,

Brown Sequard: ipsilateral paralysis  and loss of proprioception,  contralateral pain and temperature loss

Flexion tear drop fx is unstable and requires surgery

NEXUS Criteria:  Midline posterior tenderness, intoxication, nl mental status, focal neuro deficits, intoxication

Canadian Rules: Severe mechanism of injury, age>65, extremity paresthesias,  able to rotate head 45 degrees.

Strangulation injuries should probably be admitted to observe for noncardiogenic pulmonary edema and delayed blunt laryngeal  (pt will have hoarseness and significant anterior neck pain) injury.

Carotid injuries can cause Horner’s syndrome.  

BRIAN FORT  DENTAL EMERGENCIES

32 teeth in the adult mouth.   Start counting at upper right posterior molar.   Finish at lower right posterior molar.  

Primary teeth 6 months to 6 years.

Pericoronitis: inflammation of gingival overlying erupting tooth.

ABX for mouth organisms use PCN, Augmentin, Clindamycin.

Dental Caries and Pulpitis: Tx with abx and pain meds

Temrex in our dental box can be used to cover dental carie.  

Apical Periodontitis: fluid or abscess around root of tooth.  ABx treatment

Ludwig’s Angina: infection around teeth can extend into soft tissue planes in neck.

Periodontal abscess: starts from gingival margin.   ABx, drainage, pain meds

ANUG: due to anaerobes.  Patients with lowered immune response are more prone to this.   Also stress, poor sleep and other things can predispose.   Pain/ulcerated interdental papillae/bleeding gingiva.  Cholorhexidine rinses and abx.

Postextraction Pain:  less than 48 hours post op is self limited. Treat pain.  Greater than 48 hours think dry socket.   Topical anesthesia, irrigate socket,  oil of cloves/eugenol in paste or ribbon gauze gives immediate relief.

Post extraction bleeding: Tx with gelfoam, surgical, hemecon.   Local injection of lido with epi.

Ellis classification of dental trauma not used by dentists.  But ER boards do so, Class 1 enamil, Class2 dentin, Class 3 pulp.

Cover ellis 2 and 3 fx’s with calcium hydroxide paste.

Splint luxated teeth or root fx’s with Coe-Pak (zinc oxide)

Intrusive luxations should be left alone.  Don’t pull the tooth out further.  The dentist will wait to see if tooth moves down over several days.

Reimplant avulsed teeth as soon as possible.   Fluids to preserve tooth: hanks>saliva>milk>sterile saline.

Avulsed primary teeth, leave them out.  

Conference Notes 3-20-2012

CONFERENCE NOTES 3-20-2012

LAST WEEK WAS ORAL BOARDS

CARLSON   ORAL BOARD DEBRIEF

Ductal Dependent Lesions can present with cyanosis or shock.   Mottled skin is prominent in these infants.   You have to consider sepsis and do full septic work up/give abx.  Lack of fever does not exclude sepsis in infants.  Prostaglandins are indicated.  Prostaglandins can mimic sepsis.    Prostaglandins relax smooth muscle of ductus arteriosis.

Treat HUS by reducing BP, treating hyperkalemia, and transfuse for severe anemia.   Transfuse in HUS with HGB<6.   Restrict or cautious  IV fluids and consult Nephrology for dialysis.  HUS is most common cause of renal failure in kids.  Most common trigger is Ecoli toxin.   Ask for missing vital signs on the oral boards. 

Treat INH overdose with benzos, phenobarb, and pyridoxine.   Talk to family members or EMS on the oral boards.  They have key info.  INH interferes with pyridoxine which is needed to synthesize GABA.  Gyrometra muschroom (False Morel) overdose acts the same way as an INH overdose.  

If giving TPA for stroke, no heparin/asa/plavix.  If a patient is on heparin, lovenox, asa, plavix then you can’t give TPA.

AKA can develop hypoglycemia.  AKA is a starvation ketoacidosis due to emesis/gastritis.  Treat AKA with IV hydration with glucose containing fluids and give thiamine.  In aspiration setting, lateral decubitus films are classically described.  The dependent hemithorax(down side) should compress.  If it remains expanded then you need to suspect bronchial obstruction.

The lateral cspine view may be helpful in the trauma patient in shock to get quick eval for spinal fx and neurogenic shock.

Electrical Alternans is a sign of Pericardial Effusion/Tamponade. 

Abhi  Khatiyar  ORTHO STUDY GUIDE

Patellar dislocation mostly occurs in lateral direction.  Reduce patella and use knee immobiizer. 

Knee dislocation, beware popliteal vascular injury.  Examine for hard and soft signs of vascular injury. ABI<0.9 is abnormal.  All knee dislocations need angiogram. 

Tibial Plateau fx is most common fx of knee.   Lateral plateau is most common.   Beware in the older patient who has subtle or negative xray and can’t bear weight.

If you see fat globules in synovial fluid it strongly suggests fx.

Gout crystals are negatively birefringent.  Pseudogout (calcium pyrophosphate deposition disease) crystals are positively birefringent.

Thompson’s test evaluates for Achilles’ tendon rupture.   Positive test means the forefoot doesn’t move with calf compression in prone/flexed knee position. Fluoroqiunalones can increase risk of rupture.

Adhesive capsulitis (frozen shoulder).  Common complication after shoulder fx.  Can occur after stroke as well.

Carpal Tunnel Syndome: most specific sign is splitting of sensation of the 4^th finger.

Lover’s fx (Don Juan Fx)is a calcaneal fx from fall from height.  Associated injury is burst fx of lumbar spine.

Jones fx of 5^th mt is a  diaphyseal fx, slow to heal and has high incidence of non union.   Pseudo Jones Fx is an  avulsion fx’s off of the proximal 5^th mt.

ROBBIE McDERMOTT   RADIATION MEDICINE PART 2

 Tx for local radiation injury: infection control, wound care, surgical consult, nsaid’s, hyperbaric oxygen, trental, vitamin E, topical steroids.

Acute Radiation Syndrome can occur from external exposures >1Gy.  DNA damage to cells within microseconds.  Intestinal cells, lymphocytes and stem cells are most prone to injury.

Stages of ARS: prodromal/nausea and vomit, fever, conjunctivitis; latent period; illness onset; recovery or death.

Hematopoietic syndrome(2Gy)   Lymphocytes and marrow cells are most sensitive to radation.

Gastrointestinal Syndrome (6Gy)  Earlier emesis=higher exposure.  If pt vomiting in 10 minutes or less than 60 minutes=bad outcome.

Cardio/CNS syndrome (20Gy)  Not usually survivable.

2Gy and less exposure has almost 100% survival.

Cytogenic Biodosimetry=# of dicentric chromosomes gives best estimate of radiation dose.

Absolute lymphocyte count is best test in first 24 hours for estimating radiation exposure.

Irradiated patients generally do not pose a threat to care providers.  Treat medical/surgical patients first.

Time to emesis if less than 2 hours likely exposure of 3Gy and greater.   Be aware that psychogenic emesis is common with radiation event.

Triage score=N/L+E.    E=0 for no emesis,   E=2 for emesis.   N/L is neutrophill/lymphocyte ratio.  Nl =2.21  If T>3.7 radiation dose is high.

 Colony stimulating factors for exposures >3Gy.   Implement  IDSA guidelines for neutropenia.

Amylase is another marker (baseling and 24 hours) for radiatin exposure.  Amylase will increase with significant exposure.

Contaminated patients in ER need to be kept in strict isolation.  Remove patient clothing.  Wash off patient and save all fluid runoff in a closed system.  Don’t let wash fluid run down drain.

Exposed patients with no symptoms for 6-8 hours can be discharged.

ER caregivers  for contaminated patients  should wear a  whole body coverall, surgical mask, double glove.

DAVE BAROUNIS   FEIBA FOR REVERSAL OF Coumadin COAGULOPATHY

Life threatening bleeding and INR>5 use 1000U of FEIBA over 15 min plus 10mg of IV vitamin K over 30 minutes

Life threatening bleeding and INR<5 use 500U of FEIBA over 15 min plus 10mg of IV vitamin K over 30 minutes

INR should be repeated in 30 minutes.   If INR<5 then you are done.   If INR still>5 give another 500U.

JOELLEN CHANNON   M and M   Massive PE

 Massive PE: sbp <90 for 15 minutes.   Submassive PE: RV dilation on echo.  Low risk PE has neither.

Mortality is highest with massive pe and lowest with low risk pe.

McConnell’s sign: apical contraction with wall motion abnormalities away from apex.

On CT if RV diameter/LV diameter >0.9 is sign of RV dysfunction.

Elevated troponin in PEis indicative of increased short term mortality.

T wave inversion inferiorly and anteriorly is a sign of RV strain.

TPA for submassive PE may result in better RV pressures at 6 months.   No one has been able to shows mortality benefit so far in this group.

Ways to identify the sicker patient with pe: echo, shock index>1, any hypotension at all, any respiratory distress.  These patients should be strongly considered for TPA.

If high probability of PE give heparin during workup; Recommended by AHA

 No TPA for undifferentiated arrest.

Effect of respiratory depression with benzos is pronounced in patients who have some aspect of co2 retention.

LOUIS HERRMANN  PEDIATRIC HIP PAIN

Legg-Calve-Perthes (idiopathic osteonecrosis/avascular necrosis)more common in short statured male  kids.  Insidious in onset.  Lesion on xray is more common on lateral aspect of femoral head.  Conservative management usually works well

If patient has thigh or knee or groin pain gotta evaluate the hip.

SCFE  more common in 11-14 years of age.  More common in Obese kids.  Related to thyroid disease.  Kids prefer his in abduction with external rotation.   Internal rotation is painful and limited due to the altered mechanics of hip.   Klein’s line runs along lateral femoral neck and should hit the epiphysis.  Also on xray lesser trochanter will be more prominent on xray due to external rotation.   SCFE requires surgery.

Transient synovitis: most common cause of hip pain in children.  Post viral process is thought to be the cause.   Non-toxic appearing patient. May have some fever. 

Septic Arthritis: More prominent effusion compared with transient synovitis.  Can be a tense effusion.  ROM of hip is commonly exquisitely tender.  U/S can identify the effusion.   Synovial fluid with wbc count>50000 is diagnostic for septic joint.   Surgical treatment with arthrotomy and joint wash out with 2 weeks of iv antibiotics is the treatment.   4 factors are more predictive:fever, non weight bearing, elevated esr >40, wbc>12,000.

Conference Notes 3-6-2012

Conference Notes  3-6-2012

GOTTESMAN-WATTS ORAL BOARDS

Case 1:Brugada Syndrome.  More common in Asian males.  IRBBB with septal ST elevation.  Fever can elicit EKG changes.   Structurally normal heart.  It is an electrical problem.  Pt’s need an AICD

Case2: Aortic Dissection     Treated Pain well.  Thorough/Efficient  ROS and PMH.  Should give labetalol or some combination to decrease pulse pressure.  If you give a combo, give the betablocker first.  Ntg alone not best choice.  Nitroprusside is better choice with a beta-blocker .

Case3:  Flexor tenosynovitis.  Treated pain well.  Gave Rocephin.  Ring on adjacent finger should be removed.  Staph is most common etiology.  Kanavel’s sings, fusiform swelling, pain with passive

Gupta  Study Guide Trauma

Tension pneumothorax may have equal breath sounds.

CT abdomen is superior to ultrasound for diagnosing solid organ injury.

Indications for CT  for diagnosing renal injury is gross hematuria, hemodynamic instability, rapid decal injury.   Textbooks recommend In kids consider ct for microscopic hematuria.  U/S is the better test in kids in 2012 to reduce radiation.

ED thoracotomy is most likely to save a patient with cardiac tamponade due to a stab wound to the heart.

Myocardial contusion is a diagnosis that you don’t need to worry about unless the patient is hemodynamically unstable or has a significant arrhythmia.

Abdominal wall ecchymoses should raise suspicion of duodenal hematoma.  Initial CT may be neg.  Pt needs serial exams if they have continued pain.

Extraperitoneal bladder ruptures usually occur from lacerations due to pelvic fx.

LFT’s are not useful in trauma.  Pancreatic injuries may initially have normal amylase and lipase.

Most commonly injured organs in penetrating abdominal trauma:  small bowel>liver> colon.

Most commonly injured organ in blunt abdominal trauma: spleen

Treat rib fractures/contusions with pain medication and incentive spirometry. 

Left sided diaphragmatic injuries are 3X more common than right sided.   Delayed herniation is possible. These injuries do not heal spontaneously.   Best diagnostic test is laparoscopy.

Hemodynamically unstable patients due to pelvic fracture: tie pelvis with bed sheet,  next move is angiography with embolization.

EASTVOLD TOMASELLO  

ANTERIOR ISCHEMIA

Early repol: diffuse st elevation, nl r wave progression, short qt interval, nl t wave morphology, no reciprocal changes , J point notching

More likely a STEMI vs Bening Early Repol if greater ST elevation, longer QT (QTCmore than 392), lower R wave amplitude in V4 (less than 13mm).

If T Wave exceeds QRS amplitude, it suggests STEMI.

Pericarditis:  PR depression is most prominent in V5 and 6.   You will never have ST elevation with pericarditis in lead V1.   Check AVR for PR elevation.

Hyperkalemic T waves are pointed at their most superior aspect and there are flat ST segments.

Wellen’s Syndrome: Biphasic t waves leads V2-3.  Suggestive of proximal LAD occlusion.   EKG findings are seen when pt is pain free.

De Winter’s Sign:  Anterior ST depression followed by very prominent T waves.  Associated with proximal LAD occlusion.

ST SEGMENT CHANGES

  Flattened ST segment is fairly specific for ischemia

ST segment change sconcordant with the QRS  are indicative for ischemia

Subendocardial ischemia does not localize, it is diffuse.  So if you see focal st segment depression, look hard for ST segment elevation somewhere else.

Infero-lat ST depression with STE in AVR=severe left main dz or 3 vessel DZ.

If you see inferior st depression, look for ST elevation in the high lateral leads.

Millimeter criteria for STEMI will often fail you.  Look for patterns.

Localized depressions V1-3, think posterior ami.   If there is diffuse st segment depression it is subendocardial ischemia.

Isolated t wave inversion in AVL, think ensuing inferior MI.

Serial EKG’s are critical!

If ST elevation is greater in lead 3 than lead 2 in an inferior MI, that is suggestive of RV infarct as well.

Posterior MI has anterior ST depression with flat ST segments, upright t wave, and tall R waves.

Abnormal T wave balance: T wave in V1 is larger than V6 or 1.  Bundle branch blocks and LVH are the two times when this rule doesn’t work.

Pericarditis: AVR shows PR elevation and st depression,  V1 should have no pr or st changes.

RV strain=RBBB, tachycardia, T wave inversion in 3 and V3, terminal r wave in V1, S1Q3T3, 1 and AVL with upright T waves.

TCA overdose look for large terminal R wave in AVR.  Benadryl and cocaine can do the same thing.

PAILS: mnemonic for reciprocal changes  Post-Ant, Inf-Lat, Lat-Septal

Conference Notes 2-21-2012

Conference Notes 2-21-2012

TAKING YOUR PRESENTATION TO THE NEXT LEVEL WORK SHOP

CARLSON   TOXICOLOGY 3  STUDY GUIDE

Decon rat poison does not need active monitoring or treatment if a toddler has a single ingestion.   For an intentional ingestion for suicidal ideation these patients require close monitoring of INR and possibly vitamin K over several days.

Methyl chloride ingestion cause carbon monoxide poisoning

If iron ingestion has no symptoms for 6 hours it will not be a toxic ingestion.

Macrolides can prolong the QT interval resulting in torasades.  

Excessive vitamin C intake can cause kidney stones.

Methemoglobinemia is commonly due to benzocaine, or pyridium.  Pulse ox will be around 85%.   Pt will be cyanotic.  Treat with methylene blue.

Button batteries >15mm are at increased risk of impaction in the GI tract.  Button battery in the nose or esophagus needs to be removed immediately.

ORAL BOARDS   COGHLIN AND KUTKA

Case 1.  Bronchiolitis requiring intubation.  Had to trouble shoot hypoxia following intubation due to oxygen tubing becoming unplugged.

Case 2.  Guillain Barre Syndrome.   Check vital capacity.  Give IVIG.  ICU admit with neuro on board

Case 3.  CRAO.   Occular massage, breathe in paper bag, give timoptic an acetazolamide.  Consult Ophtho

RADIATION EXPOSURE MEDICINE   MCDERMOTT

Alpha particles: 2 protons/2 neutrons.  Can be blocked by paper/wall/skin.  Inhaled particles are bad.  Uranium, plutonium are sources.

Beta particles: Electrons.  blocked by plastic sheet.   Tritium, Strontium are sources

Gama Rays: Can create ionization.  Higher energy than xray. Easily travels thru matter.  Blocked by lead or thick concrete.  Can hit bone marrow, gi tract, brain.

Neutrons: Uncharged particles. Can cause another material to be radioactive.

Irradiation=exposure with no material transfer.  Contamination=material transfer.

Basic unit of radioactivity is the Curie.  1 Gray=1 sievert.

Important isotopes to know: Iradium, Cesium, Cobalt (industrial 3).   Hydrogen, Uranium, Plutonium, Americum (military 5 hard to get and enrich).

Geiger Counter measures radiation present from contamination of an area or patient.

Personal protection is fairly effective with just coveralls, gloves, and face shields. 

Decontamination of patients is best in a closed space in an isolated area of ED.

Conference Notes 2-14-2012

Conference Notes 2-14-2012

IN TRAINING ZEBRAS    GIRZADAS

STEMI CONFERENCE

Out of hospital arrests are contributing to high post- PCI mortality rate.  If patient has prolonged resuscitation, decision to go to cath lab needs to be discussed with cardiologist.

Posterior-Lateral ST segment elevation suggests circumflex artery lesion.

Cardiogenic shock after cardiac arrest is a strong marker for eventual death.

Concordant st elevation with a bundle branch block is very suspicious for AMI.   Similarly, “ironing out” or straightening of the st segment is also very suspicious for an impending stemi. 

You shouldn’t see a Q wave in lead 1 in a LBBB.

DOCUMENTATION   McGURK

Document that you visualized and interpreted  the imaging study you ordered.  

TRAUMA GSW TO TORSO NON-OPERATIVE MANAGEMENT  PATEL

Pt has to have hemodynamic stability and no peritonitis to be considered for non operative management.   Also cannot have signs of hollow viscous injury on CT.

Serial abdominal exams are required.  This has the best sensitivity and negative predictive value for intra-abdominal injury.   Serial lab testing is also required.

Laparascopy is used for penetrating LUQ injuries to look for diaphragmatic injuries.

Some Trauma research has shown success with non-operative management of penetrating torso trauma.

FAST exam has little utility for penetrating abdominal trauma.  It is too nonspecific.  Blood could be coming from solid organ injury.  It is useful in penetrating trauma to the chest to rule out pericardial tamponade.  

Negative lap carries a lifetime risk of 15% for SBO.

CASE F/U  AFIB WITH RVR  COLLANDER

Afib with RVR: 60% convert with 100J biphasic.   80% with 200J biphasic. 200 J is a reasonable starting dose of electricity.   Use synchronized cardioversion.

Predisposiing factors for Afib: rheumatic heart, htn, etoh binge drinking, ischemic heart disease, obesity.  Fish oil may decrease risk.

Who should be cardioverted?  Unstable, first episode, infrequent episodes, worsening symptoms.

Who should not be converted?  Asymptomatic, elderly with multiple comorbidities, bleeding risk, symptoms more than 48 hours.

If you get them back into sinus, they can go home without meds.

Ottawa Protocol:  1 gram of Procainamide over 1 hour first,  if not successful cardioversion with 200J.

No need for anticoagulation following successful cardioversion.

If you fail with cardioversion, you can re-try with pt in exhalation, or use disconnected paddle to press zoll pad down more firmly.

Elise's conference pearls from 1-17 (also sent via email)

From Study Guide:

1.  Neutropenic fever and rectal exams:  7th Edition Tintinalli does say digital rectal exam is relatively contraindicated in neutropenic patients, and should be withheld until after antibiotics are started.  It also says to pay attention to the oral exam, perianal exam and entry sites of IV catheters; areas of infection not commonly evaluated in non-neutropenic patients.

2.  Coagulopathy and paracentesis:  7th Edition Tintinalli also says to reverse coagulopathy and thrombocytopenia before doing paracentesis, so correct answer for the test, but probably not the correct answer in real life:

Hepatology. 2004 Aug;40(2):484-8.

Performance standards for therapeutic abdominal paracentesis.

Grabau CM, Crago SF, Hoff LK, Simon JA, Melton CA, Ott BJ, Kamath PS.

Source

Advanced Liver Diseases Study Group, Division of Gastroenterology and Hepatology and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.

Abstract

Large-volume paracentesis, the preferred treatment for patients with symptomatic tense ascites due to cirrhosis, has traditionally been performed by physicians as an inpatient procedure. Our objectives were to determine (1) whether large-volume paracentesis could be performed safely and effectively by gastrointestinal endoscopy assistants and as an outpatient procedure, (2) whether the risk of bleeding was associated with either thrombocytopenia or prolongation of the prothrombin time, and (3) the resources used for large-volume paracentesis. Gastrointestinal endoscopy assistants performed 1,100 large-volume paracenteses in 628 patients, 513 of whom had cirrhosis of the liver. The preprocedure mean international normalized ratio for prothrombin time was 1.7 +/- 0.46 (range, 0.9-8.7; interquartile range, 1.4-2.2), and the mean platelet count was 50.4 x 10(3)/microL, (range, 19 x 10(3)/microL - 341 x 10(3)/microL; interquartile range, 42-56 x 10(3)/microL). Performance of 3 to 7 supervised paracenteses was required before competence was achieved. There were no significant procedure-related complications, even in patients with marked thrombocytopenia or prolongation in the prothrombin time. The mean duration of large-volume paracentesis was 97 +/- 24 minutes, and the mean volume of ascitic fluid removed was 8.7 +/- 2.8 L. In conclusion, large-volume paracentesis can be performed safely as an outpatient procedure by trained gastrointestinal endoscopy assistants. Ten supervised paracenteses would be optimal for training the operators carrying out the procedure. The practice guideline of the American Association for the Study of Liver Diseases which states that routine correction of prolonged prothrombin time or thrombocytopenia is not required is appropriate when experienced personnel carry out paracentesis.

____________________________________________________________

3.  From GI Curbside Consult:  IV erythromcyin now well accepted pre-endoscopy, and probably better than NG in cleaning out upper GI tract to help with visualization:

Aliment Pharmacol Ther. 2011 Jul;34(2):166-71. doi: 10.1111/j.1365-2036.2011.04708.x. Epub 2011 May 25.

Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding.

Bai Y, Guo JF, Li ZS.

Source

Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.

Abstract

BACKGROUND:

Studies evaluating the effect of erythromycin on patients with acute upper gastrointestinal bleeding (UGIB) had been reported, but the results were inconclusive.

AIMS:

To compare erythromycin with control in patients with acute UGIB by performing a meta-analysis.

METHODS:

Electronic databases including PubMed, EMBASE and the Cochrane Library, Science Citation Index, were searched to find relevant randomised controlled trials (RCTs). Two reviewers independently identified relevant trials evaluating the effect of erythromycin on patients with acute UGIB. Outcome measures were the incidence of empty stomach, need for second endoscopy, blood transfusion, length of hospital stay, endoscopic procedure time and mortality.

RESULTS:

Four RCTs including 335 patients were identified. Meta-analysis demonstrated the incidence of empty stomach was significantly increased in patients receiving erythromycin (active group 69%, control group 37%, P<0.00001). The need for second endoscopy, amount of blood transfusion and the length of hospital stay were also significantly reduced (all P<0.05). A trend for shorter endoscopic procedure time and decreased mortality rate was observed.

CONCLUSIONS:

Prophylactic erythromycin is useful for patients with upper gastrointestinal bleeding to decrease the amount of blood in the stomach and reduce the need for second endoscopy, amount of blood transfusion. It may shorten the length of hospital stay, but its effects on mortality need further larger trials to be confirmed.

4.  From Joint Peds/EM conference:  This is just a reiteration of an excellent point made during the discussion:  for healthy, self-limited new onset seizure in peds patient, NO emergency neuro-imaging needed unless: focal neuro deficit, prolonged altered state, fever, or focal seizure.  If the kid needs an emergent neuro-imaging study due to one of these reasons, MRI far preferable.  All kids will get EEG, try to arrange within 24 hours for improved predictive value, and EEG results will guide need for outpatient MRI.

Conference Notes 1-17-2012

Conference Notes 1-17-2012

JOINT  EM-PEDIATRIC CONFERENCE     SEIZING CHILD

Simple Febrile Seizure:  6mo to 6 years, generalized tonic clonic sz lasting less than 15 min, no focality, pt has temp >38.     Consider blood glucose level.   LP is not mandatory.  Approach child as having no seizure at all and look for source of infection with history and physical exam.   Don’t get a CT brain on these kids.   Admit if child has more than 1 sz in 24 hours or any sign of complex febrile seizure.  If seizure does not occur in first day of illness this could be a red flag and consider admission.  Similarly, if first febrile seizure occurs after the age of 5 the pt should have a neuro eval inpatient or outpatient. 

First Non-Febrile Seizure:  Careful clinical exam for any focal neuro deficit.  Labs should be ordered based on individual clinical circumstances.   UTox should also be considered.  EKG should  be done only with a history of syncope.  No EKG needed if seizure is focal.   LP only with concern about meningitis.  EEG is a recommended outpt option in all these kids.   EEG within 24 hours is best if possible but don’t go nuts trying to get this arranged from the ER.  Focal seizures, Todd’s paralysis, not returning to baseline within a few hours  all require an ED CT. If you can get the radiologist to do the MRI do that instead of CT.  Kids with first time generalized seizure with no focality, no Todd’s paralysis, and no  failure to return to baseline do not need ED imaging.  Seizures in kids who are on seizure meds don’t need imaging even if seizures have some change in character from usual or child has trivial head injury. If child returns to normal after seizure they can go home and get outpt work up.   Admit kids with first time seizure who are under 6mo.  

 Status Epilepticus:  First line is Benzos,  Second line: Fosphenytoin.    Can give phenobarb 5-10mg/kg prior to getting level if patient is on phenobarb at home.    Third line: IV Keppra,   IV Depacon.    Fourth line: Propofol.     If kids get to the ED per EMS or family still seizing that in effect is status.    Loading levels for all seizure meds Is 20 mg/kg.

Sudden Unexplained Death in Epilepsy:  More likely in patients whose seizures are poorly controlled.   Adults more common than kids.    Adults:1:650,   Kids 0.2:1000

HAYWARD   HEME-ONC  STUDY GUIDE

RDW changes prior to MCV in deficiency anemias.

Platelet deficiency usually shows up as petechiae, epistaxis, mucosal bleeding, but not deep tissue bleeding.

D-Dimer can be normal in liver disease but should be very abnormal in DIC.  Thus it can differentiate between the two. 

Low platelets is the most common lab abnormality in DIC.

Most common cause of DIC is sepsis

In hemophilia give factor 8 prior to getting imaging study done.   50 international uinits for possible head bleeds (100% of factor activity),  and 25 IU for joint bleeds (50% of factor activity).

DDAVP is mainstay of treatment for kids with type 1 von Willebrand Disease.

Hemolysis due to transfusion reaction will result in decreased serum haptoglobin, increase ldh, increased serum hemoglobin and hemoglobinuria.   Increased LDH and low haptoglobin are 90% specific for hemolysis.

TTP= thrombocytopenia, MAHA, fever, renal impairment, and neurologic impairment.

Treatment of TTP is plasma exchange.

GROMIS-RADAWI  CURBSIDE CONSULT GI BLEED

Black stool means digested stool. It passed through small bowel.   90% Started above the ligament of treitz.    10% can come from right colon.   Melanotic  is an incorrect term.  Melenic is the correct term.  Hematochezia is 90% colonic bleed but 10% have upper gi source.   That 10% is at high risk of shock from an arterial bleed in an ulcer.

Medications in GI bleed are secondary to identification of major bleeder and circulatory support.   Use of PPI’s in GI bleed started from data showing that blood clotted better in stomach when ph was higher.  Most GI bleeders don’t need continuous PPI drip.  Major league bleeders should probably be on continuous drip.

NG tube can be helpful to assess the pace of bleeding.   There are false negatives however.  Helps to better visualize GI tract with endoscopy.   Varicies do not contra-indicate NG tube placement. 

IV Erythro can be used to induce gastric motility and improve the endoscopic visualization of the stomach and small bowel.

ANDREA CARLSON    POISONING WITH CV DRUGS

Class 1a: Quinidine is prototype.   Procainamide is more common.    Infusions can result in hypotension and QRS widening.    Disopyramide is a strong negative inotrope.  Blocks pancreatic islet cells resulting in hypoglycemia.    QRS widening/QTC prolongation due to sodium channel blockade.    Tx with Bicarb for QRS widening.   Avoid acidosis.  Prolonged resuscitation is indicated.   You can try lidocaine (1b).

Class 1C: Flecainide and Propafenone.   Strong NA channel  blockers.  Effects are hypotension, bradycardia,  QRS/QT prolongation.  Flecainide can cause Brugada Pattern.   Tx with Bicarb.  For propafenone follow up with hypertonic saline.  Amiodarone (Class 3), lipid rescue, and pacing may help.

Class 1A/1C Mimics: TCA’s, cocaine, phenothiazines, Benadryl, tegretol, choloral hydrate, propoxyphene.

Class 1b:  Lidocaine and Mexiletine.    Also NA channel blockers but selective for rapidly depolarizing or ischemic cells.   At times used as a cutting agent for cocaine.  Can cause methemoglobinemia.    Fasiculaitons and seizures can result from bigger OD’s.  Treat seizures with benzos or phenobarb.   Don’t use phenytoin because it is a 1b also. 

Class 3: Amiodarone acts at the potassium channel.   Sotalol is a potassium channel blocker and beta blocker.   Tx is supportive for these.   Glucagon may benefit sotalol OD.   Multaq (Dronedarone) is a new Class 3 drug but has a lot other properties (dirty drug).

Adenosine is unclassified drug.   Increases AV nodal refractoriness.   No reports of overdose.  Use lower dose in cardiac transplant patients and those using persantine.     Increase dose in patients on methylxanthines.    Caution in asthmatic patients theoretically could induce bronchospasm.

BILL SCHROEDER    CONCUSSION/HEAD INJURY EVALUATION

SCAT2 :   Ask the head-injured player questions about this game and the last game.    Do the standing tandem gait balance test for 20 seconds.   More than 5 adjustments in that 20 seconds requires pulling the kid from the game.

After head injury, kids need rest with no physical activity or school until symptoms resolved without Tylenol/ibuprofen.    Limit video games and texts.    80-90% of concussions will resolve in 7-10 days.

Post-traumatic headaches can be treated with amitriptyline.  Topomax if there is a history of migraines.

Sertraline helps with cognitive effects following head injury.     Other medications possible are Ritalin and Concerta.

Step wise progression for return to play.  Don’t even start until symptom free.   As the patient increases activity, if symptoms recur they need to rest for 24 hours and restart at lower level.

Children should not return to play the same day as concussion because they are more prone to cerebral edema in “second impact syndrome”.   Only 2 cases in adults.   Seen basically only in teenagers.   Rapid death 2-5 minutes after second impact.  Peak incidence of second impact syndrome in the mouse model is 3 days out from first injury.

Concussion is due to stretching of neuronal and axonal membranes. Ion influx then other bad oxidative and metabolic stuff in the nerve cell.

RESIDENT SELECTION COMMITTEE MEETING

Conference Notes 1-10-2012

Conference Notes 1-10-2012 (sorry but they are abreviated due to lecture/admin responsibilities this day)

BAROUNIS/KONICKI    ORAL BOARDS

Case 1: Hypothermia requiring active rewarming with cardiopulmonary bypass or cool guard catheter.   The patient needed a low measuring bladder thermometer to accurately identify the patient’s temperature.

Case 2:Intussusception

Case 3: Perilunate dislocation

JIM MALETICH   VERTIGO

MAGGIE PUTMAN  /NICK KETTANEH   5 MIN F/U’S

GIRZADAS   NURO STUDY GUIDE

ALYSSA   AV  BLOCKS

Lyme disease can cause third degree heart block.

3^rd degree is defined by AV dissociation.

Weinkebach is 1^st degree type 2.  PR progressively lengthens and then a qrs is dropped.  The RR interval shortens as the pr lengthens.

INNAUGURAL EM-IM CASE  CONFERENCE

Patient had critical Upper GI bleed due to varicies.

NG tube is not contraindicated by known varicies.

Give blood, octreotide,protonix,antibiotics,  iv fluids, reverse INR  with ffp/vitamin k if increased.

80+% of  upper GI bleeds will be due to gastritis or pud.   If you suspect varicieal bleeding (the minority) based on physical exam or lab testing, start octreotide.

Variceal bleeders with upper GI bleed have a 50% mortality.

Cirrhotics have a baseline hyperdynamic cardiovascular state.  They may have low bp at baseline due to being chronically vasodilated.

Chronic treatment with any beta blocker in a patient with varicies lowers portal pressure and decreases chance of rebleeding of varicies.   The target heart rate is bradycardia in these patients.   Cipro is used prophylactically to decrease risk of SBP.    Cipro does not worsen liver disease induced coagulopathy like it does for warfarin induced coagulopathy.

Give variceal bleed patients prophylactic antibiotics.  It has been shown to decrease rebleeding an mortality.

Intubate these patients with ramped or head up position.   Pre-oxygenation is critical.   Use a neuromuscular blocker to optimize your view.    You can also try using a meconium aspirator to improve your ability to suction.    LMA can be a bridge device.

In coding cirrhotic patient be concerned about hypokalemia and hypomagnesemia.

Conference Notes 1-3-2012

Conference Notes 1-3-2012

CARLSON  TOXIC ALCOHOLS

Ethylene Glycol:  Metabolized to oxalic acid that can cause renal failure. Severe metabolic acidosis  can cause Kussmaul respirations. 

Calcium oxylate can cause renal tubular necrosis.

Presumptive diagnosis with ph <7.3, bicarb <20, Osmolar Gap>10, Urinary oxylate crystals. 

Definitive DX= serum EG level

Osmolar Gap: 2Na + BUN/2.8 + Glucose/18 + ETOH/4.6.   Nl OG is -14 to +12

Rough EG Level= Osmolar gap X 6.2

To get an EG level you gotta order it stat and make sure the lab call Quest Lab to pick it up.  Gotta follow up on it!

Other causes of elevated osmolar gap:propylene glycol (iv ativan, iv dilantin), acetone, mannitol, sorbitol, ivp dye, glycerol from scope mouth wash.

Anion Gap= Na-(CL + Hco3)

EG poisoning urine may show calcium oxylate crystals (50%) or flourescence.

TX: NaBicarb to keep ph over 7.3, Mag, Calcium, Fomepizole to inhibit ADH,

Indications for Fomepizole: EG level >20, Early suspicion + OGap >10,  Late suspicion + 2 presumptive criteria.

Fomepizole dosing: 15mg/kg up to 1 G followed by 10mg/kg Q12 hours x 4 doses  then 15mg/kg Q12 hours.  Reduce interval to Q4 hours during dialysis.   Increasing acceptance of using fomepizole  as monotherapy without dialysis.  Criteria for monotherapy is ph>7.3, modest anion gap, no renal dysfunction, adequate supply of fomepizole.  Kids are better candidates for monotherapy than adults due to metabolism differences, but adult could possibly use this therapy as well.   Headache is a common side effect of Fomepizole.  Patients with significant acidosis will need dialysis.

ETOH Therapy: Only use if no access to Fomepizole.  It can cause hypoglycemia in kids. 

Also give pyridoxine when treating EG poisoning.

Methanol:     Dermal and inhalation exposure can be significant.  Metabolized to formic acid which goes to eyes and can cause blindness.   Patients will have CNS depression and vision disturbances.  Renal function should remain normal.    Classic CT/MRI finding is basal ganglia hemorrhage.   Two things can cause that finding CO and Methanol.

TX: Folate, Dialysis, Fomepizole.  Fomepizole can be used as monotherapy with same caveats as noted above for EG poisoning.

ISOPROPANOL    Very intoxicating.  Patients will have Osmolar gap with elevated serum acetone and ketonuria.   Patients won’t have significant acidosis.  May have GI bleeding.

CHASTAIN/ANNEKEN  ORAL BOARDS

Case 1:Type A Aortic Dissection.   Think dissection with sudden symptoms above and below diaphragm.  BP was low due to early pericardial fluid.

Case2: Fight Bite.  Should give IV Unasyn promptly.   Pt needs admission for IV ABX and Hand Surgery.

Case3:Hypertensive Encephalopathy/Seizure  from cocaine overdose.  TX with hi-dose benzos and nipride or nicardipine.

KUTKA   PENETRATING NECK INJURIES

Current mortality is 3-10%.   Laryngotracheal injury is 20% and

Zone 1: sternal notch to cricoid cartilage

Zone 2: circoid to angle of mandible

Zone 3:above the angle of mandible

Anterior and posterior triangles are bisected by SCM.

Brown Sequard: Hemi section of cord with ipsilateral hemiplegia and loss of pain and temperature sensation on contralateral side.

Can get Horner’s syndrome in Zone 3 injuries.

Evaluating for trachea-laryngo injuries can be done with CT.  

Evaluate for Pharyngo-esophogeal injuries with CT, esophogram, endoscopy.

Evaluate for vascular injuries with CTA. Can also use color flow Doppler but it is operator dependent and some vessels have a limited view.

Controversy on surgical vs non-invasive management of Zone 2 injuries.   Most Trauma centers will do noninvasive work up for  Zones 1 and 3.  

MISTRY  ADMIN  UPDATE

Please give feedback on new cordless speculums.

Were are collecting data on ED thruput for the government (CMS).    Please fill out specific Blue section of Dr. Note in IBEX as soon as you have an admit discussion with an attending.

New Electronic Med Record  Kick Off tomorrow in 190W.

New Admission Process.   For uncovered admits transfer attending call to 4590 so they can give admit orders.

KESSLER   CONSULTATION  IN THE ED

We lack training in communication and consultation in undergrad and graduate medical education.

Important components of a consultation: organized, prompt, pleasant, polite.   #1 is Be Nice!

Small talk helps alittle.  It builds relationships.  Be cautious with this.  The consultant may be in a hurry.

Prior to speaking with a consultant, know your choices, gather up all the data, decide what your question or direct need is.

5C’s of Consultation

contact: identify yourself and the consultant

 communicate: concise and accurate of clinical picture

 core question: what’s the question/need of consultation

 collaborate: open to and incorporates consultant’s recommendation

 close the loop: Review and repeat patient care plan, Thank consultant

 Be sure to document your conversation.

Behavioral Profile: Get other people to do what you want them to do and be happy about it. 

The Platinum Rule: Treat others the way they want to be treated.

Consultant personality types: Open/Guarded     and   Indirect/Direct

Tailor your style of consultation to the specialty of the consultant.

Use problem solving and creative thinking to get what the patient needs.

Practice is important to perfect your consultation style.  

Conference Notes 12-20-2011

Conference Notes 12-20-2012

VIJAY    ANO-RECTAL DISEASES

Thrombosed external hemorrhoids: elliptical incision.  Thrombosed hemorrhoid should be firm, tender, and purple.   Bleeding should be minimal.   You will express clots from your elliptical incision.  Sitz baths following procedure.

Anal fissure: Tx with sitz baths, stool softners, cautious nitroglycerine topically, anal hygiene.

Rectal FB:  Try passing foley beyond fb and slowly pulling fb out of rectum.

KATANNEH   STATUTORY RAPE

Consensual sexual  relations between individuals that would be legal except for their age.

Statutory rape is linked with increased suicide and lower academic achievement in victims.

In Illinois any sexual contact involving a person less than 17 and accused is 5 years older.

We are required to report if we suspect that the child has been a victim of abuse. This does not include a consensual sexual relationship with a boyfriend or girlfriend.  You could get sued by parents however.

If the older person is responsible for the younger person’s welfare such as a teacher, you have to report that. 

BARTGEN   M AND M

Osteomyelitis of sternoclavicular joint.

Metacognition=thinking about how we think

Decision making strategies: Heuristic or pattern recognition.   Systematic or hypothetico-deductive or Bayesian is reliable but slow.   Algorithmic method is used for high risk time dependent scenarios like codes.  Worst case scenario rule out method.  

Biases:

Pattern recognition suffers from anchoring and confirmation bias

Rule out worse case scenario suffers from value induced  bias.  This bias is expensive an we overutilize resources.   Decsion rules help with this bias

Hypothetico-deductive method suffers from premature closure bias.

Bias defenses:  awareness of biases, stay skeptical, question your diagnosis, consult in uncertain situations

Identify risky discharges: abnormal vitals, elderly, poor access to care,  patients that had another recent evaluation, patients that worry you, high risk complaints,  communication errors, rare problem.

71% of bounce backs had a resting tachycardia on the first visit.

Address abnormal vital signs with additional thinking, testing, observation, and arranging follow up.  Read the notes in the chart from nurses and other staff and EMS. 

Specific, clearly written discharge instruction are your last defense against bad outcomes.

LAMBERT  U/S GUIDED VASCULAR ACCESS

U/S decreases your time required to do a central line and decreases complications as well.   It also works well for perioheral lines.

Gotta use a high frequency linear probe to do vascular access.  It has better resolution in the near field.

Can use tegaderm to provide sterile coverage on the probe if you can’t find a sleeve.

To see needle on screen it has to be in a 1.5mm cut of the probes beam.

Keep indicator on the probe to the procedure performer’s  left.  The probe indicator should also be in same direction as the dot on the screen. 

Keep probe perpendicular to skin.  For right IJ, the probe should be just superior to clavicle with medial edge of probe near medial end of clavicle.

Make sure IJ collapses with probe compression.

The Sonosite machines in our department have a soft ware enhancement that greatly highlights the needle on U/S.  You have to be in the vascular program to use this feature.

When you tent the vessel with the needle, Mike recommends making a jab with needle to puncture thru the vessel.  If you tent to far though you can jab thru the back wall of the vessel.  So jab just when you begin to tent the vessel.

For peripheral lines use the basillic vein.  It is the largest vein above the elbow.   You will need a longer angiocath due to the distances involved.

Bedside U/S for DVT

Best view of the CFV is at or below the great saphenous junction with the CFV.   If patient has clot to both vessels, Mike recommends consulting vascular as this is a higher risk scenario.

Pop on top=popliteal vein is more superficial than popliteal aretery.

DVT study you need to visualize the CFV and make sure it compresses and visualize the popliteal vein and make sure it compresses. Get a 5cm sample of views at both sites.   Make sure the clip you save shows complete compression at both sites.

Augmentation: Seeing back flow in the popliteal or CFV with calf compression does not rule out dvt.   It just means that the vessel is not completely occluded. 

LAMBERT  VASCULAR  ACCESS LAB

Conference Notes 12-13-2011

Conference Notes 12-13-2011

STUDY GUIDE QUESTION SLAM    Endocrine

Target HGBA1C is currently 7%.  Tighter control lower the risk of end organ disease from dm but increases the risk of hypoglycemic episodes.

Treat mucormycosis with amphotericin B.  Mucormycosis on boards is typically a black eschar on the nose.

1 amp of D50 (25g of sugar) will raise blood sugar by 100mg/dl.

ACEI’s are effective in slowing the progression of diabetic nephropathy regardless of effect on BP. Blocking angiotensin 2 is the key.

Treatment of oral hypoglycemic overdose includes IV dextrose and /SubQ/IV octreotide.

DKA treatment keys: Insulin, IV fluids,  close monitoring and treatment of Potassium/Hypokalemia.

Treatment of AKA is D5.9NS.  AKA will have an anion gap acidosis.  Cerebral edema is not a risk in AKA because pt’s are not hyperosmolar like DKA patients. 

With hyperglycemia, the serum NA should decrease 1.6 for every 100 increase in glucose.

Myxedema coma TX: IV dextrose containing fluids, water restriction for hyponatremia, passive rewarming, steroids for secondary hypothyroidism/adrenal insufficiency,  IV levothyroxine, treat precipitating factors.

Amiodarone can cause thyroid dysfunction including hypothyroidism and thyrotoxicosis.   Lithium can cause hypothyroidism.

Adrenal insufficiency can lead to hyperkalemia and peaked t waves on EKG.  Hyponatremia is also possible.   Tx  is iv fluids containing dextrose, IV hydrocortisone, vasopressors.

LAM  SIDS/ALTES

Most difficult thing is explaining what happened to the parents.

SUID: sudden unexpected infant death.  Occurs in infant less than 1yo who was well before.   SIDS can be said when after autopsy, no cause is identified.

Risk Factors: young mom, maternal drug use/smoking,  inadequate prenatal care,  prematurity, low birth rate, higher birth order.  Prone sleeping position, bed sharing, exposure to cigarette smoke, febrile illness, overheating,  no pacifier.

Pathophysiology: interaction of genetic and environmental factors.   Autonomic dysfunction, decreased arousal/gasping response to hypoxia or hypercarbia.   Cardiac ion channel defects.  Abnormal cytokine responses to infection.

Home electronic monitoring has not been shown to reduce the incidence of SIDS

Infant back sleeping has decreased SIDS by 50%.   Get all soft materials out of crib.

NO ROSC after 30 minutes of resuscitation has survival rate of less than 1% (0.2%).  No patient who received greater than 2 doses of epi survived.

SIDS Questions to ask: medical hx, family hx, social hx of mom, when last seen child alive,  anything unusual about infant in last 24 hours.   Who placed child down, who found child.   There is a CDC website on SIDS.

ALTE: more common in premature, mortality is about 1%.    Etiology is most commonly idiopathic.  3-5 times  higher risk for SIDS but risk is still quite low. Link is tenuous between ALTE and SIDs.   5-10% overlap of ALTE and SIDS.  The Back to Sleep Campaign had reduced SIDS but no ALTE.

LOVETT  M and M  

Rectus sheath hematoma is due to damage to superior or inferior epigastric arteries, or direct tear of rectus sheath.   Usually self limiting unless pt is anticoagulated.  Advanced age increases risk of mortality.

Retroperitoneal bleed: incidence of up to 0.6% of anticoagulated patients.   Diagnosis is frequently delayed.  Treat by reversing anticoagulation.   IR may need to be consulted if bleeding is post procedural.

Sign outs:  Leaving MD can call back in one hour to check for problems in the signed out patients. Root cause of 24% of malpractice claims is sign out problems.  Sign out is involved in 80% of medical legal liability cases.

CARLSON  PEDS TOX

#1 cause of death is analgesics.  #2 batteries,  #3 Hydrocarbons, #4 Plants, #5 cough/cold preps, #6 fumes like CO, #7 pesticides,  #8antidepressants.

Child Resistant:  Less than 15% of kids can open it in 5 minutes.   Then less than 20% of kids can open it even after being shown how to open the lid.   It is not “child proof”

Teen top picks: Etoh, prescription opioids, marijuana.

Munchausen by proxy: Parent gives insulin or sedative to child to make them look sick. Parent wants to go to hospital to get attention for themselves.

Serious overdoses:

 CCB’s  diltiazem, verapamil and amlodipine are worst.    Don’t discharge patients with this OD. 

Camphor is dangerous but camphor concentrations are limited by law in vapo rub and camphophenique that can’t kil a kid.  Camphor moth balls are hard to find and the other forms of moth balls are less toxic.

Clonidine and visine (clonidine in a bottle)  cause opiate-like toxidrome

TCA’s: amitryptiline and imiparmine are the worst

Opioids: worst are long acting forms=methadone, oxycodone.  Lomotil  (diphenoxylate and atropine) is very dangerous due to cns and respiratory depression.   Dextromethoraphan may cause agitation but is not a respiratory depressant.

Oil of wintergreen is very dangerous due to it’s high concentration of methylsalicylate.

Sulfonylureas: increases insulin release and suppresses glycogenolysis.  Effects are delayed and prolonged and can be severe.   Admit for observation.

Toxic alcohols: If a child swallows some you need to eval and observe.  If they only licked to substance there should be no toxicity.

Cyanide

Hydroflouric acid

Colchicine is a disaster.  Shuts down cellular function causing gi failure

Paraquat: Oxygen is contraindicated

Amanita phylloides

Don’t worry: brodifacum, chlorox bleach, acei’s/arb’s, diuretics, cholesterol meds, antibiotics, otc camphor products, motrin, h2 blockers, actos, avandia.

You don’t need to give charcoal to kids at any time.  High risk of aspiration.  

JAKUBOWICZ   DKA in Kids

DKA can be initial presentation of type 1 dm 30% of the time and type 2 dm 10% of the time.

DKA produces more beta hydroxyl buterate than aceto acetate.  Urine testing measures acetacetate.   A mnemonic to remember which ketone predominates is,  pt’s with DKA get a “B” for their glucose control, not an “A”.

Cerebral edema: accounts for up to 87% of dka deaths.   Associated with low arterial CO2 and high bun, iv bicarb use, young age, and severe acidosis.  Cause could be osmotic or ischemic.  Diagnosis is a clinic one prior to CT (headache, vomiting, lethargy)  Treat with decreased IV fluids, give mannitol, consider hyperventilation. 

Hypokalemia: In DKA there is a total body depletion of potassium.   Start supplementing if K is less than 5.5.

Fluid use in Peds DKA: Unclear if volume of fluids affects incidence of cerebral edema.  No link between insulin bolus and cerebral edema.   Basically don’t bolus fluids or insulin in DKA. 

Conference Notes 12-6-2011

Conference Notes 12-6-2011

URUMOV   STUDY GUIDE  ENVIRONMENTAL EMERGEN CIES 2

Sorry I didn’t take great notes for this one.  I was just absorbing the info.

Treat hydrofluoric acid burns with calcium gluconate gel or bier block or intra-arterial calcium gluconate.

Exercise does not protect you from high altitude pulmonary edema or other altitude illnesses.

HAPE:  first finding is rales in RML 2-4 days after ascent.  Pt has marked dyspnea on exertion.  Treat with nifedipine,  cialis.  Descent also is therapeutic. 

HACE: Most sensitive physical finding is cerebellar ataxia.   Medical treatment is steroids.   Probably more important is to descend.

Mushroom poisoning toxicity can be estimated by the time of onset of symptoms.   If vomiting starts after 6 hours toxicity is likely.

Aminita phylloides and Gyromytra case 50% of mushroom toxicity.  Both cause liver toxicity.

Poison Ivy:  Leaflets of 3, beware of me.  Urushiol is the chemical culprit.  Spread by direct contact, indirect contact, airborne.  Fluid in bullae does not contain urushiol.  Tx with IvyBlock, wash skin and clothes, symptomatic treatment, systemic steroids for severe cases.

Inocybe and Clitocybe  mushroom poisoning is treated with atropine.   You get SLUDGE syndrome.

Electrical cord bite injury can result in delayed labial artery hemorrhage.

Kauranoparalysis: transient paralysis from lightning strike

Digitalis containing plants: Foxglove, Oleander, Lily of the Valley. 

BADILLO   ACLS MEGACODES

Supraglottic airway is recommended as initial airway management.

Unstable VT: altered mental status, hypotension, chf,  ischemic chest pain, or other signs of shock.

Diagnosing VTach: Fusion beats, capture beats, av dissociation, or concordance.

New recommendation for VTach: Procainamide.

Tx for polymorphic v-tach: Defibrillation acutely,  mag for torsades,  isoproterenol for brugada.  Could also try overdrive pacing.

Afib with WPW will have an extremely fast ventricular rate.   Synchronized cardioversion is the way to go.   You may need higher doses of electricity.  More powerful defibrillator is in the cath lab if needed. Procainamide also can be tried but it takes some time.   Mag bolus can also be tried.

Energy doses:  regular rhythm 100J     Irregular rhythm 200J

In cardiac arrest, Amiodarone is your first choice as an anti-arrythmic.   Give 300mg.

VF or Pulseless VT: shock/cpr/epi or vasopressin/amio. 

No atropine, bicarb, pacing, calcium in cardiac arrest.

BAROUNIS   EMERGENT REVERSAL OF NOVEL ORAL ANTICOAGULANTS

4 UNITS OF FFP is needed to reverse Coumadin.  This amounts to a liter.  This costs $1000.

ACMC has FIBA but no PCC’s.

The INR of FFP=1.5.

Rivaroxaban is an oral 10a inhibitor, like oral lovenox.

Factor 7, 10, 2 are the ER important factors.

Coumadin inhibits 7, 10.   Factor 7 drives INR.

Heparin inhibits factor 10.  Lovenox inhibits 10a

Pradaxa is a direct thrombin inhibitor.   Renal excretion.

Pradaxa inhibits thrombin production.

If PTT is nl in a patient on pradaxa then don’t work on reversing pradaxa.  There is no benefit.

PCC (prothrombin complex concentrates)  we don’t have this at ACMC.   3 factor PCC has a lot of  factor 2,9,10 and some Factor 7.   4 factor PCC also has a lot of factor 7.

PCC’s reversed PTT in volunteers with rivaroxaban.  No effect with volunteers on pradaxa.

Protamin (manufactured from salmon sperm) is indicated for reversal of heparin and also less so for lovenox.

Novo 7 is recommended for reversal of pradaxa (dabigatran) based on animal studies.  Very expensive because multiple doses are required.  (@$50,000)  Novo7 has risk of thrombotic complications.  No proven human benefit for reversing head bleed.

FEIBA (factor 8 inhibiting bypassing agent) is in the ER at ACMC.  It has factors 2,7,9,10.   $1600/dose.   Dose at 500-1000units.  Works to reduce !NR within an hour.   No mortality benefit, but did show reduced hematoma expansion  in ICH.  Most of the data is for reversing warfarin. 

Recommendations:

Pradaxa Bleed   check ptt is <1.5X normal=no action needed.  Can give FEIBA or FFP and dialysis.

Rivaroxaban Bleed  give FEIBA or PCC’s

Warfarin Bleed   4u FFP or FEIBA

Bottom Line:  Consider using FEIBA for all you critical bleeding patients that require reversal.

KERWIN  LOUGHLIN   ORAL BOARDS

Case 1: Endocarditis: Empiric treatment is Vanco and Gent, add nafcillin and rifampin for IVDA

Case2:Carotid dissection:  Can result from neck trauma, sudden twisting, stretching.  Think about with complaint of head and neck pain.    Manage with IV heparin.

Case3:Sickle Cell related stroke: Treat with exchange transfusion.

Test Taking Points:  Moved expeditiously thru the cases.

MED STUDENT REVIEW

VILLANO    METHEMOGLOBINEMIA

Ferrous iron is oxidized to ferric iron.   There is equipoise usually in the body between ferrous and ferric iron in hgb.    Methemoglobinemia is an increase in the ferric form.

Risk Factors: Dapsone, benzocaine spray, nitrites/nitrates, pyridium, sulfonamides, amyl nitrate, auto exhaust, poppers, analine dyes, and smoking.

Suspect methemoglobinemia if: cyanosis not susceptible to 100% o2, chocolate brown blood, lactic acidosis.    Also in real life and on boards think about methemoglobinemia if the pulse ox is around 85%.

ABG with Co-ox: look for gap between O2 sat and Co-ox measurement.

Tx with methylene blue in symptomatic patients or if methem level is >20%.   Not recommended for children under 6 years old.   If you have a young kid consult tox and use a low dose.  

Other considerations: exchange transfusion or hyperbaric oxygen therapy

Admit: if you use meth blue put them in the unit.   Can go home if level comes down to <15% without methblue. 

LOVETT   PI UPDATE

EICU attendings will be following patients waiting for MICU bed.

There are CHF and Asthma protocols in PICIS Forms.

Sign out culture : be sure to review labs prior to signing out

Bounce back report being developed.

SAYGER    ADMIN/PT RELATIONS

I was not present for this lecture unfortunately

Conference Notes 11-29-2011

CONFERENCE NOTES 11-29-2011

DR. TATOOLIS  LVAD EMERGENCIES

3 types of LVAD.   Most common type is HeartMate 2 which is currently the only FDA approved device.

The pump is valvless. If pump fails, pt has in effect severe AI.

Hi BP decreases the flow in the pump.   So most patients have their BP maintained around 80 systolic.

The motor is extremely reliable.  The most common failure points are external.   

The internal motor cannot be imaged with CT/Xray/Ultrasound

To determine BP in LVAD patient you have 3 choices.  Assess mental status,  get bp with cuff and Doppler, put in an art line.

You can’t always believe the interrogation info you get from the pump computer.  The pump can be clotted and still get nl flow values.   To get an assessment of how the pump is working, you need an echo to assess the sizes of the RV and LV.

Common complications: bleeding (20% have GI bleeding to AV malformations/also acquired von willibrand’s dz due to shear forces in pump. Treat GI bleed with FFP and not Vitamin K), clotting, infection (drive line infection/endocarditis), malfunction (treat this like a spine injury and don’t move the patient once you find a position of the patient and the device that works), RV failure

LVAD  patient with a severe headache is very likely going to have a head bleed.   Get them on Nitroprusside to lower the BP as much as the patient can tolerate.

CT scan is the study to evaluate for infection in the chest around the device.  Get study without contrast.  You are looking for fluid around device.

In cardiac arrest, CPR should be done as in a normal person.

Sometimes, in cardiac arrest and LVAD is working, the LV can get sucked down like a prune if all the blood has been pumped out of the LV.  The RV gets distended like a beach ball.   This results in severe dysrythmias.  The answer is to turn down pump.    If you are having dysrythmias, do a bedside echo to see the size of the ventricles.

Life expectancy of patient with LVAD is 90% at 1 month, 70% 1 year, 60% 2 years,  two longest living are 7 years.

Bottom line on sorting thru LVAD emergencies: talk to the patient,   figure out their bp with a Doppler,  get an echo to assess LV and RV size.

GIRZADAS    BREAKFAST WITH THE RLT

FACULTY     OPHTHALMOLGY LAB

Conference Notes 11-22-2011

Conference Notes 11-22-2011

CHANNON-PAQUETTE  ORAL BOARDS

Case1:  CO Poisoning with cardiac ischemia.  Treat with hyperbaric oxygen.  NTG for chest pain.   Also give ASA.

Case2: Hip Fracture

Case 3:Temporal Arteritis.  Consider DX in patient with headache over 50.  ESR is commonly over 50 with this diagnosis.   Treat with oral prednisone.

Test Taking Comments: Thorough ROS and Organized efficient Physical Exam.  Need to really push to get thru the three cases on time.  As the examinee, you have to take on a take charge demeanor.

CUMMINS   SHOULD PARAMEDICS INTUBATE?

Asking paramedics if they should be intubating in the field is viewed as an attack on their core skill.

Paramedics have been shown to be very competent in getting the ET tube in the trachea.  (@90-95% success rate)

However,  field intubations have been shown to increase mortality when compared to BVM.

Intubation is frequently followed by unintentional hyperventilation.   Which can worsen outcome.  Intubation may delay or interrupt chest compressions.

Average paramedic does  1-5 intubations per year.

If paramedics are going to intubate a patient with cardiac arrest in the field, they cannot interrupt chest compressions, they cannot miss an esophageal intubation, and they  cannot over-ventilate.  Those three things will worsen outcomes.

GIRZADAS  INTUBATING THE OBESE PATIENT

Obese patients desaturate more rapidly than normal weight patients

RAMPED Postion will improve oxygenation and laryngoscopic view.

Consider Ketamine sedated laryngoscopy prior to/in place of  RSI.

Bag-valve-mask ventillate using two handed/two person technique.  Also use CPAP valve on bag-valve-mask.

If you can't get the tube, try using an intubating LMA as your go-to rescue device.    ASA recommended.   

DR. SILVER   INITIAL CARE OF THE ACUTE CHF PATIENT

 The number of admissions for CHF a patient has is inversely proportional to life expectancy.

Approach to the CHF patient

Step 1:NYHA Functional Classification of CHF:   1=no symptoms,   4=symptoms at rest,  2 and 3 =somewhere in between.

Step 2: Assess  volume and perfusion.   Dry/wet   warm/cold

Step 3: Figure out their medications.  Diuretics for volume control.  Digoxin 0.125mg as a neuro hormonal depressor.   ACEI,  ARB’s

Step 4: Make an assessment of how sick they are.   Systolic BP/ CR/BUN are predictors of in-hospital mortality .   Seattle Heart Failure Risk is an iphone app.

Step 5: Integrate all the above info.

Be judicious with iv diuretics.   They can increase mortality/los.

NTG is a wonderful drug for CHF.  It lowers systemic and pulmonary vascular resistance.  Also lower wedge.  Gotta use enough of it.  Monitor patient and titrate up based on patient response.

Aldosterone antagonists are expected to be more commonly used.  A side effect is hyperkalemia.

In the hypotensive chf pt you need inotropes/diuretics.  Use milrinone for the tachycardic patient. Use dobutamine in the patient without tachycardia.

BNP can be not super high in copder’s and obese patients despite them being in decompensated chf.

Consider  ace-I’s in hypertensive chf patients.

No role for nesiritde in acute decompensated heart failure.

TOERNE   ACUTE ETOH WITHDRAWL

Brain responds to chronic etoh exposure  by altering receptors for glutamate and gaba.   The GABA related receptor affects Chloride influx into the cell.    Gaba receptor decrease and phenobarb receptors increase in the face of chronic etoh exposure.

Earliest withdrawl syndrome is Seizures.  Less than 3% of seizures result in status epilepticus.   30% of withdrawl seizures progress to DT’s.  

Next syndrome is uncomplicated withdrawl

Alcoholic hallucinosis is diagnosis of exclusion.  More likely is DT’s

Delerium Tremens occurs 2-7 days after stopping etoh.  Key is delirium.  They also have hyperadrenergic surge.   Risk factors are heavy daily eoth use, previus dt’s, older age, concurrent medical illness, abnormal liver function.

Proof is twice percentage of etoh.   151 rum is 75.5% etoh.  

Labs that suggest etohism: anemia with mcv around 105 which is a marker of folate deficiency.  Others are hyponatremia, thrombocytopenia.

Treat DT’s with large dose benzos and Phenobarbital.    Benzos increase the frequency of Chloride  channel opening and phenobarb increases the duration of channel opening. 

Give phenobarb 260mg slow ivp every 10-15 minute.  

Ketamine may be helpful to antagonize the glutamate receptor.

Conference Notes 11-15-2011

Conference Notes 11-15-2011

ANDREJ   ENVIRONMENTAL STUDY GUIDE

Altered mental status differentiates heat exhaustion from heat stroke.

Most effective way to cool patient is evaporative cooling.   Stop cooling once you have patient at 39 degrees.

Pricky heat: Sweat glands get blocked, histamine release, itchy rash.  Treat with antihistamines and talcum powder.

Acclimatization to heat: early onset of sweat production, increased plasma volume, decreased sweat electrolyte concentration, lower heart rate and increased stroke volume.

Most marathoners have a tropnin leak that is not prognostic of adverse outcome.  They can go home.

Dapsone may be effective in brown recluse spider bites.   Controversy about this.

Coral snake: red on yellow kill a fellow, red on black venom lack.  Elapid snake with neurotoxin venom.  Any bite gets antivenom for a coral snake.

Rattlesnakes: Crotalid snake,  triangular head, elliptical pupil, retractible fangs, pit anterior to eye.  Antivenom for spread(progression of localized symptoms)/bled (coagulopathy)/almost dead(abnormal vitals).

Antivenin is not contraindicated in pregnant patients.  It is not weight based.  Starting dose is 5 vials.  May need to redoes antivenin.

Spikey toxins use heat to deactivate toxins.   Slimey toxins use acetic acid.

Life threatening jelly fish are the box jelly fish and Portugese man-o-war.

Cold related EKG findings: Osborn waves, slow v-fib, bradycrdia,  t wave inversion, long pr and qt intervals,  afib,  muscle tremor artifact.

 Cerebral arterial gas embolus (CAGE).  Usually occurs within 10 min of surfacing. Vertigo, and altered mental  status are most common symptoms.   Recompression therapy is the only definitive treatment. Use saline to fill ET tube cuff when sending a patient to hyperbaric treatment.

Most common malady of scuba divers is ear squeeze (Barotitis).

Decompression sickness: Type 1  is joints/skin.             Type 2 is pulmonary, cv, neuro, vestibular.

Chillblain: inflammatory lesions of skin caused by long term intermittent exposure to damp, nonfreezing conditions.

Ophthalmia nodosa is a chronic ocular manifestation after exposure to tarantula spider hair

BADILLO/SINNOT   ACLS MEGA CODES

We covered the management of SVT, AFIB, WPW and Vtach, V-fib and Torsades.

DR. BERKLEHAMMER   VASCULAR DISEASES OF THE GUT

Mesenteric ischemia: Think about this in htn, smoking, dm, afib, post-mi.  You usually have double or triple vessel disease to have ischemia.  Check lactate. Diagnose with CTA. Tx with surgery or embolectomy.

Venous mesenteric ischemia has insidious onset.   Think about It in portal htn, hypercoaguable state, malignancy.  Dx with iv contrast CT. Tx with heparin.

Ischemic colitis: Sudden onset Abdominal pain with passage of mostly blood clots  per rectum. Usually will have lateral abdominal  tenderness.  You don’t need angio for colonic ischemia.  Only need angio for small ball ischemia.

Cholesterol  emboli following  cardiac cath can also cause mesenteric ischemia.

SAYGER/McGURK   ED CODING

For HPI you need 4 elements for a level  5.

For ROS you need 10 systems elevated for a level  5.

For PMH/SH/FH  you need 2 of 3 for a level  5.

Need 8 organ systems from physical exam for level 5.

Please make note of your medical decision making by noting test results, treatments and ekg/imaging interpretations.

Fortunate   (4-2-10-8) is the mnemonic for remembering what you need for  HPI-PMH/SH/FH-ROS-PE elements to get a level 5.

GROMIS and DRs. BAHN and AVULA  CURBSIDE CONSULT  AFIB

Get a  troponin on all new onset afib patients or any pt with afib and chest pain.

Important to start heparin or lovenox on all new afib patients in ER.

Consider d-dimer if  considering pe as cause of afib.   TSH should also be obtained in new afib patients.

Consider cardioversion for rhythm control for  young person with lone afib of less than 24 hours,  hemodynamically unstable afib,  patient with paroxysmal afib who is on Coumadin an comes in with afib.   

Any patient with rhythm conversion (chemical or electrical) requires warfarin for 4 weeks.

Rate control target is less than 110 beat per minute.

Ibutilide is best conversion drug.  Chemical cardioversion works better with afib less than 24 hours.

CHADS2 score.   (CHF 1, HTN 1, AGE >70 1, Diabetes 1 , Stroke or embolic phenomenon 2 )Less than 1 you don’t need warfarin and can use asa alone.  2 or more you need warfarin.  If score is 1 could be asa, plavix, dabagatrin, or warfarin based on physician judgment.

Ablation is 95% curative for a flutter.     

Conference Notes 11-08-2011

Conference Notes    11-8-2011

STEMI CONFERENCE

Some code 60’s are very tough calls.  

STUDY GUIDE  TOX   ANDREA CARLSON

Asymptomatic kids who ingested  sustained released verapamil need admission.

Eating a cigarette by a kid will not cause significant nicotine toxicity.  It will only cause vomiting.  Eating a tobacco plant is more likely to cause toxic nicotine levels.

NAC increases glutathione supply, detoxifies NAPQI and enhances microvascular function.   It can also scavenge free radicals.     

NAC is equally effective if given at any time in the first 8 hours after ingestion.   So you can give AC and wait until you get a 4 hour APAP level.

LSD gives you synesthesias which are you can taste sounds or feel  sights.    MDMA (ecstasy) causes bruxism.   Think of Ravers using pacifiers.

Glucagon increases CAMP to overcome beta blocker toxicity.

Things that cause wide QRS (quinidine effect): TCA’s, Carbamazepine, Propoxyphene, Benadryl, Cocaine 1a’s (PDQ: procainamide/disopyramide/quinidine), some 1c’s(encainide/flecanide).   All also have an an anticholinergic appearance to their toxidrome.

Avoid the interation between clarithromycin and digoxin.  Will increase risk of digoxin toxicity.

Intubation of patients with salicylate toxicity is fraught with hazard due to need for hyperventilation to maintain relatively normal ph.

Insulin in the setting of calcium channel blocker toxicity acts by providing glucose to myocytes for energy.

Glucagon causes emesis.

All antidotes work for CCB and Beta Blocker overdose: atropine, glucagon, high dose insulin.

Pepto Bismol contains asa.   Oil of wintergreen has a lot of asa (methyl salicylate)in it.  Ben Gay has oil of wintergreen in it.

Caffeine competes with adenosine at the adenosine receptor.   Also theophylline competes at the adenosine site.

ORAL BOARDS    RICCARDI  and KATIYAR

Case1:Splenic/renal  artery aneurysm rupture in a pregnant woman.  More common in multips due to repeated progesterone/estrogen fluxes in pregnancy.  Treat hemorrhagic shock.

Case2: ASIS avulsion.  Treat conservatively with pain control and crutches.

Case3: ASA toxicity.  Treat with fluids/bicarb drip/dialysis.   ABG with metabolic acidosis and respiratory alkalosis.    Important to give potassium when al

Comments on technique of examnee: Good pace.  Thorough exam.  Increase blood type and cross to 4-6 units.  Important to do a FAST at the bedside.  Once you identify intraperitoneal fluid you are going to OR.  Good to  Start transfusion.

Difficult cases.  Good rapid review of systems.  Good to ask about appearance of injured extremity.   Good nv exam of injured extremity.

PATIENT AUTONOMY      SHAYLA GARRET-HAUSER

Great read on medical ethics: The Immortal Life of Henrietta Lacks

Non malficience, justice, beneficence, patient autonomy are the pillars of Medical Ethics.    Hippocratic Oath only covers the first three pillars.

Voluntary consent to procedures did not become a medical concept until the Nuremburg Code post WW2.

Autonomy is a right to non-interference, not a right to every requested medical treatment . Doctors are not obligated to provide treatment they consider of no benefit.

There is a power/knowledge differential between doctor and patient.   Thus we control option that are offered to patients.   We need to understand patients values to know how to tailor their options.   

 Nothing trumps the MD in charge of a resuscitation.  If MD feels it is futile, the MD can stop resuscitation despite family wishes. 

Case discussion on should you perform drug testing on a 15yo patient who refuses test and parents demand it.     No one in auditorium will forcibly obtain urine from patient. But if patient voluntarily gives urine most would do test.    Same with pelvic exam or other evaluation.  The bright line for most MD’s in the room was if you have to forcibly restrain/sedate pt to get some evaluation done, they would not do it.

MED STUDENT REVIEW

Conference Notes 10-25-2011

Conference Notes 10-25-2011

EM-EDS JOINT CONFERENCE   MANAGEMENT OF HEMATOLOGIC  ILLNESSES

If patient has fever and clinically has acute chest syndrome  give ABX ASAP irregardless of CXR findings.  Antibiotics in a sick febrile patient with SCD can be lifesaving.

Acute Chest Syndrome: Dispo can be floor or PICU depending on clinical picture.  Transfusion is also dependent on clinical picture.  Decision should be made in concert with hematologist.

Supplemental oxygen should be given routinely in acute chest syndrome.   Supplemental oxygen does not need to be given routinely in painful crises.

TTP is rare in the pediatric population. 

ITP Management: Don’t give steroids without consulting hematologist.  There is controversy about steroids prior to bone marrow biopsy.  At ACMC hematologists rarely give steroids intially. Concern is that steroids may obscure diagnosis of leukemia.    IVIG is more commonly given by hematology.   Treat if mucosal bleeding.  These patients tend to have worse outcomes.  WinRho is similar to rhogam.  Can only give to Rh pos patients.  WinRho can’t be given in anemic patients.   Algorithm: If mucosal bleeding or platelets around 10-20K  give IVIG if there is a response that is confirmatory of ITP. In subsequent events give dexamethasone.    In a child with platelets less than 50K and head injury get CT.

Leukemia:  Check PT/PTT because APL versions of AML can cause DIC picture.  If leukemia presents with respiratory distress think T-cell or Burkett’s or Lymphoblastic.  There may be a mediastinal mass due to these.   IV fluids are critical to preserve renal function.  Be alert for tumor lysis syndrome with high potassium, uric acid and phosphate.   If febrile over 101 give abx for neutropenic fever.     Think leukemia in a child with bone pain, pallor,  splenomegaly, persistent lymphadenopathy, normocytic or macrocytic anemia, or any cytopenia.   Steroid use in a patient presenting with symptoms due to leukemia can delay diagnosis and it may alter the leukemia that requires a more toxic chemo regimine.

STUDY GUIDE  QUESTION SLAM TOXICOLOGY

Urinary alkalization for ASA and chlorpropamide.  3amps of NaHCO3 in 1L of D5W and run at 200ml/hr.  Shoot for a urinary ph of 7.5-8.5.   Monitor the K closely.

For TCA OD  Look at AVR on the EKG an look for a wide,tall  terminal R wave.  Treat seizures due to TCA’s with benzos and phenobarb.    TCA’s have sodium channel blockade,  alpha blockade, gaba antagonism,  and anticholinergic properties.   IV Sodium Bicarb for QRS widening or arrhythmia.

Most common finding in Serotonin Syndrome is myoclonus.   Tx: remove offending agents and give cyproheptadine.

MAOI  with severe hypertension tx with short acting antihypertensives.  There is risk of severe hypotension with long acting antihypertensives.   If ingested more than 1mg/kg, the patient should be admitted to ICU.   Beta Blockers  are contraindicated.

Tyramine reaction: severe occipital or temporal headache within 90 minutes of dietary amine ingestion in patient on MAOI. 

Neuroleptic Malignant Syndrome:  Magnesium for prolonged QT to avoid Torsades.  External cooling is indicated.  Benzo’s can help rigidity.   Use rocuronium for intubation instead of succinylcholine.  IV fluids and supportive management is indicated.  Dantrolene may be tried.

Lithium Overdose: Tx with saline and Kayexelate. Next step for severe overdose is dialysis (lithium >4, sustained release preps, increasing level, level not improving with saline and kayexelate).   EKG may show long QT, st depression and t wave inversion.   Treat seizures with benzos.  Don’t use phenytoin.

 Number 1 factor related to respiratory depression with a benzo is another coingestant.   Cirrhosis may also increase risk.

Isopropyl alchol: Fomepizole is not indicated because acetone is not more toxic than isopropanol.   Upper GI Bleed is classic finding.   Hemodialysis for severe overdose.

Naloxone drip rate for massive opioid overdose (body packer) is 2/3 of the initial effective bolus dose per hour.  Be prepared for a very agitated patient on waking.

Highest risk of ACS with cocaine use is in a chronic regular user.  (90% of cases).  Men more common.  ACS usually occurs within 3 hours of use.   Cocaine also increases athrogenesis.

MARK HINTON   TOXIC ALCOHOLS

Ethylene Glycol  is metabolized to toxin glycolic acid and oxalic acid (calcium oxylate crystals in kindey).

Osmolar Gap= 2X NA + Glucose/20 + BUN/3 +ETOH/5.  Should be less than 20.

Methanol Toxicity is metabolized to formic acid.  Formic acid causes acidosis and vision loss.

TX for EG and Methanol:  ETOH or Fomepizole.  Fomepizole has less side effects (less gi irritation, cns depression and hypoglycemia).   All patients should get dialyzed.   IV bicarb can be used for acidosis.  Folic acid supplement for methanol.   Pyridoxine for ethylene glycol.

Isopropanol:  Severe cns intoxication,  risk of gi bleed and hypotension.  Less toxic  than methanol and ethylene glycol.   Metabolized to acetone.   In kids check for hypoglycemia.   Elevated osmolar gap.  No severe acidosis.  “Ketosis without acidosis”  Treat with supportive care.

DAN NELSON  CHEST PAIN IN KIDS

Dangerous Causes: ACS, cardiomyopathy, arrhythmia, PE, pneumothorax, aortic dissection,  mediastinal mass, perforated esophagus,  perforated ulcer.

Ask about family history of sudden death or connective tissue disorders.

Benign early repolarization: Consider  in the following groups: young, male, African American.   ST-T segments are concave up.

Juvenile T wave pattern: females more common than males.  Normal up to 8yo, or into adolescence in athletes.  T wave inversions v1-3.

Sinus arrhythmia causes variation in HR with respiration.

Long QT syndrome: Can be related to certain meds.  500ms is definitely abnormal

Hypertrophic Cardiomyopathy: Consider when ekg shows lvh.  Big S waves anteriorly and Big R waves laterally.

WPW: Short pr interval with delta wave.   Orthodromic conduction has narrow complex.  Antidromic  conduction causes wide complex.

Brugada syndrome: Due to a genetic sodium channel abnormality.

CHRISTINE KULSTAD   FAST TRACK EMERGENCIES

Skin tears:  If skin will approximate use steristrips to close, and cover with non-adherent dressing. If there is more tissue loss try adaptic or hydrogel/duoderm.  Hydrogel or duoderm can stay in place for one week.    You can use tissue adhesive as well for wounds with little tissue loss.

Absesses: Give pre-procedure pain meds/sedation.   Give anesthesia twice.  Initially in skin on roof of abscess then make incision and relieve pressure. Then give anesthesia to remainder of abscess cavity.  No evidence that irrigation improves outcome.   Don’t need sterile gloves.  Probably safe to irrigate with tap water instead of saline.   Use U/S.    Needle aspiration is not effective.   Probably safe to not pack small abscess in otherwise healthy person.   Don’t need to pack abscess tightly.  Pack loosely.  Don’t need iodoform gauze.   Can use any type of ribbon gauze.   

DAB KAMAN-MALLABAN  PATIENT FALLS

Number of fall in ACMC 50-60 falls per month.

If we don’t  decrease our number of falls, we will lose reimbursement dollars.   It is important to work as a team to prevent falls.

Communicate with nurses, leave cart rails up, give patients opportunities to toilet, walk them to bathroom.  

If patients have a yellow wrist band they are a high fall risk. 

New Motto  “No one falls”

Injury Potential from Fall:  Age,  Bones (osteoporosis, cancer),  Coagulation (Coumadin, plavix)

Obviously it is important to make sure you have the correct patient and correct labeling of all specimens.

Do a time out before all procedures.   It is a Red Rule.  

DAVE BAROUNIS      THERAPUETIC HYPOTHERMIA PROTOCOL   ICEP PRESENTATION

Previous research has shown improved outcomes in cardiac arrest patients.

56 month period of study at ACMC.  

Inclusion: ROSC from any rhythm

Goal:  Get temp to 33 degrees C in 4 hours.  Cooled for 24 hours.

Results: 160 patients with ROSC.   73 with ROSC were excluded.   The most common rhythm was V-Fib.  Overall Mortality for patients treated with hypothermia was 70%.     Good Neuro  Outcome (CPC 1-2) of survivors treated with hypothermia  was 14%.    In patients treated with normothermia 71% died but good neuro outcome was  4%.   Various sub groups were analyzed.

Conclusion:  In unwitnessed arrest there was no benefit from hypothermia.  In witnessed V-Fib arrest there was survival and neurologic benefit from hypothermia.

Conference Notes 10-18-2011

Conference Notes 10-18-2011

ROHIT GUPTA/DAN BARTGEN  ORAL BOARDS

Case1:Retro/parapharyngeal abscess in a child.  Give ABX and consult ENT for I and D.

Case2:Iatrogenic Perforated Bowel.  Emergent surgical consultation.

Case3:COPD exacerbation complicated by a pneumothorax. Place chest tube.

JOAN COGLIN  STUDY GUIDE ENT

Most common source of bleeding in posterior nosebleed: sphenopalatine artery.

Complications of posterior nasal packing: hypoxia, cardiac arrest, obstructed airway, necrosis of collumella

Ludwig’s Angina is a complication of a dental infection.  Soft tissue swelling under tongue. Intubate early to protect airway.

Lemierre’s syndrome: Septic thrombophlebitis of IJ.  Severe sore throat, fever, and neck pain.  Patients can develop septic emboli to lungs. Fusobacterium species are most common cause.

Auricular burns need non-emergent referral to burn center.  Chondritis is common.  No silvadene above clavicles due to skin discoloration.

Floxin otic solution is the only FDA ototopical abx approved for use with perforated tm.  Floxin otic is very expensive.   Cortisporin otic suspension is second choice and is less expensive so more commonly used. 

Don’t use carbonic anhydrase inhibitors in sickle cell patients with hyphema.  CAI’s will lower ph in anterior chamber and increase sickling.  

 Malignant Otits Externa is most commonly due to pseudomonas.  Usually in adult diabetics.

CRAO: treat with digital massage, IOP lowering meds and paracentesis, Rebreathing to raise pco2 and vasodilate.

Aphthous stomatitis is due to allergic reaction to unidentified trigger.  Usually on labial or gingival mucosa.  Tx with steroid swishes.  Betamethasone syrup.

Orbital cellulitis: pain with eom, most common cause is sinusitis usually ethmoid,  most common cause is staph aureus and strep.

Optic Neuritis: Eye pain, altered vision, optic disc edema. Tx with iv steroids.   Think MS.

 Dental concussion: tooth is tender but not mobile

Subluxation: tooth is tender and mobile

Luxation: tooth is displaced

ANUG: acute necrotizing gingivitis treat with metronidazole and chlorhexidine rinses

Last ditch procedure to stop life threatening posterior epistaxis is lido/epi

DAVE BAROUNIS  VENTILATORS

Ideal Body Weight is almost always somewhere between 50 and 80 kg.

Tidal Volumes can be 6-8cc/kg. 

 In asthmatics start with a low respiratory rate of 8 to avoid stacking breaths.  Can be 12-16 in a normal patient.

Be sure to titrate your patients pAO2 to between 70 and 200max.   If pAO2 is  above 200 at 4 hours there is increased mortality

5 common causes of hypoxia: low fio2,  hypoventilation, impaired diffusion, shunting, V/Q mismatch such as pneumonia/pulmonary edema/ARDS

PEEP stents open the alveoli.   PEEP reduces preload and afterload in CHFer’s.

Peak airway pressure mostly dependent on resistance of airways because this is calculated to the power of 4.

Trouble shoot a patient with High Paw (level of bronchial tubes/trachea): disconnect the vent and evaluate how hard it is to bag.  If pt is hard to bag the airway not the machine is the cause.  Listen to patient, suction, get a CXR.   Next check Plateau Pressure (level of alveolus).  If no change then there is some type of obstruction such as aspiration or bronchospasm or secretions.  If PP increases could be due to abdominal distension or autopeep)

In asthmatics you have to use low rate, small tidal volumes, and prolonged time for expiration to avoid stacking breaths.  You are willing to tolerate a ph of 7.1-7.2 as long as oxygenation is ok. 

Similar strategies for COPD.  In addition only give enough fio2 to keep sats just over 90%.  Higher o2 sats will diminish COPDer’s respiratory drive.

There is an ARDS Network scale to Titrate FIO2 and PEEP.

ACMC has capability to use ECMO for both kids and adults.

Acidotic patients need A LOT of ventilation.   Pt’s can arrest peri-intubation if you don’t keep ventilating them during induction somehow.   Think bagging or bipap ventilation during sedation and paralysis.

PAARUL CHANDRA    TRAUMA LECTURE PELVIC FX’S AND GU TRAUMA

Pelvic fracture with shock has a 35-50% mortality rate

Single break is usually stable. Two or more breaks is unstable.

CT of abdomen/pelvis is considered GOLD STANDARD for  diagnosing pelvic fx’s.

Main issue with pelvic fx’s is hemorrhage control.  Resuscitate with generous blood products, stabilize the pelvis with sheet wrap.   If still unstable, next move may be angiography to embolize an arterial vessel.  If patient is unstable there is usually arterial bleeding.

Most common organs injured with pelvic fx are bladder and urethra.

When considering GU trauma, don’t place foley prior to urethrogram.  If foley already in place, leave it in place.

If urethral tear is partial, some contrast will get into bladder.  If complete, no contrast in bladder.

There is greater risk of bladder injury when trauma occurs with full bladder.

2 types of bladder rupture: intra and extraperitoneal.  Intraperitoneal are treated with surgery. Extraperitoneal are treated with foley catheter.  

Bladder injury symptoms: gross hematuria, inability to void, suprapubic pain.  DX with retrograde cystography.

Renal injuries are graded 1-5 with 5 being most severe (shattered kidney). Grade 1 0% go to surgery. Grade 2, 15% have surgery. Grade 3, 76% have surgery.   Grades 4 and 5  increase from there.   There is also renal pedicle injury.